An approach to the design of brain-penetrating histaminergic agonists

DOI: 10.1016/0223-5234(93)90135-2

Source and publish data:

European Journal of Medicinal Chemistry p. 201 - 211 (1993)

Update date:2022-08-17

Topics:

Authors:

Young Young

Ganellin

Griffiths

Mitchell

Parsons Parsons

Saunders

Sore Sore

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Article abstract of DOI:10.1016/0223-5234(93)90135-2

Known and novel histaminergic H₁- and H₂-receptor agonists were investigated as potentially potent and selective brain-penetrating compounds. Structural modifications were introduced in an attempt to favour passive diffusion across t

Full text of DOI:10.1016/0223-5234(93)90135-2

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