2-p-Tolyl-1h-imidazo[4,5-f][1,10]phenanthroline and its Co(II), Ni(II) and Cu(II) complexes 219
ligand and the complexes. Further, antibacterial activity Co(II) complex was found to be
significant effect against all bacteria. In contrast no effect was observed against P. aeruginosa.
The very high antibacterial activities of the ligand, Cu(II) complex and the Co(II) complex could
be further studied for the treatment of infections caused by any of the above organisms.
CONCLUSION
In this study, imidazole and phenanthroline containing 2-p-tolyl-1H-imidazo[4,5-
f][1,10]phenanthroline (L) and its complexes were synthesized and characterized. The analytical
data, physical and spectroscopic studies suggest that the complexes were of the general formula
[M(L)2Cl2].nH2O where M is Co(II), Ni(II) and Cu(II) and n corresponding to M is 1, 2, 2,
respectively. According to the IR data of the compounds, L is coordinated to the metal ions
through nitrogen atoms of the C=N (phenanthroline ring) groups. The biological activity test
results showed that the ligand and its metal complexes have good antibacterial activity against
the bacterial strains except for Ni(II) complex. We think that the ligand and the two metal
complexes (Cu(II) and Co(II)) might be effective as antibacterial agents.
ACKNOWLEDGEMENT
We would like to thank Firat University, Elazig, Turkey, for the financial support.
REFERENCES
1. Chalk, S.J.; Tyson, J.F. Anal. Chem. 1994, 66, 660.
2. Samnani, P.B.; Bhattacharya, P.K.; Ganeshpure, P.A.; Koshy, V.J.; Satish, N. J. Mol. Catal.
1996, 110, 89.
3. Bachas, L.G.; Cullen, L.; Hutchins, R.S.; Scott, D.L. J. Chem. Soc., Dalton Trans. 1997, 9,
1571.
4. Fussa-Rydel, O.; Zhang, H.T.; Hump, J.T.; Leidner, C.R. Inorg. Chem. 1989, 28, 1533.
5. Pickup, P.G.; Osteryoung, R.A. Inorg. Chem. 1985, 24, 2707.
6. Sammes, P.G.; Yahioglu, G. Chem. Soc. Rev. 1994, 23, 327.
7. Calderazzo, F.; Pampaloni, G.; Passarelli, V. Inorg. Chim. Acta 2002, 330, 136.
8. Larsson, K.; Öhström, L. Inorg. Chim. Acta 2004, 357, 657.
9. Binnemans, K.; Lenaerts, P.; Driesen, K.; Görller-Walrand, C. J. Mater. Chem. 2004, 14,
191.
10. Lenaerts, P.; Storms, A.; Mullens, J.; D’Haen, J.; Görller-Walrand, C.; Binnemans, K.;
Driesen, K. Chem. Mater. 2005, 17, 5194.
11. Williams, A.F.; Piguet, C.; Bernardinelli, G. Angew. Chem. Int. Ed. Engl. 1991, 30, 1490.
12. Hurley, D.J.; Tor, Y. J. Am. Chem. Soc. 2002, 124, 3749.
13. Felder, D.; Nierengarten, J.F.; Barigelletti, F.; Ventura, B.; Armaroli, N. J. Am. Chem. Soc.
2001, 123, 6291.
14. Connors, P.J.; Tzalis, J.D.; Dunnick, A. L.; Tor, Y. Inorg. Chem. 1998, 37, 1121.
15. Camren, H.; Chang, M.Y.; Zeng, L.; McGuire, M. E. Synth. Commun. 1996, 26, 1247.
16. Bolger, J.; Gourdon, A.; Ishow, E.; Launay, J. P. Inorg. Chem. 1996, 35, 2937.
17. Lehn, J.M.; Ziessel, R. Helv. Chim. Acta 1988, 71, 1511.
18. Coyle, B.; Kwanagh, K.; Mcxcann, M.; Devereux, M.; Geraghty, M. Biometals 2003, 16,
321.
19. Qizhuang, H.; Jing, Y.; Hui, M.; Hexing, L. Mater. Lett. 2006, 60, 317.
Bull. Chem. Soc. Ethiop. 2013, 27(2)