European Journal of Medicinal Chemistry p. 241 - 244 (1994)
Update date:2022-08-30
Topics:
Leuschner, J.
Schaefer, H.
Leuschner, F.
A series of totally aliphatic 3-(acyloxy)propanolamine derivatives were prepared and their pA2-values were determined employing the guinea-pig atrium.Compounds, with an acetyl or methyl succinoyl half ester moiety showed a pronounced β1-adrenergic blocking activity.Keywords: 3-(acyloxy)propanolamines / β1-adrenergic blocking activity
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