On the metallation of 2-isopropylpyridine

DOI: 10.1016/S0040-4020(98)00507-9

Source and publish data:

Tetrahedron p. 8771 - 8782 (1998)

Update date:2022-08-11

Topics:

Authors:

Pasquinet, Eric

Rocca, Patrick

Marsais, Francis

Godard, Alain

Queguiner, Guy

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Article abstract of DOI:10.1016/S0040-4020(98)00507-9

2-Isopropylpyridine has been successfully metallated and functionalized by using potassium diisopropylamide (KDA). Subsequent functionalization has been achieved with a wide range of electrophiles and good to excellent yields have been obtained. The action of other potassium or sodium bases has also been investigated.

Full text of DOI:10.1016/S0040-4020(98)00507-9

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