Tetrahedron Letters p. 1049 - 1052 (1999)
Update date:2022-08-11
Topics:
Barluenga, Jose
Fananas, Francisco J.
Sanz, Roberto
Fernandez, Yolanda
Treatment of N-(2-bromoallyl)-N-methyl-2-fluoroaniline with tert- butyllithium affords 1,3-dimethyl-4-lithioindole, via intramolecular addition to a tethered benzyne intermediate. Further reaction with electrophiles leads to 4-functionalized 3-methylindol
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