Journal of Organic Chemistry p. 641 - 646 (2014)
Update date:2022-08-11
Topics:
Wang, Long
Ren, Zhi-Lin
Ding, Ming-Wu
A one-pot synthesis of multisubstituted 2,3-dihydro-1H-2-benzazepin-1-ones and 3H-2-benzoxepin-1-ones by an I-MCR/Wittig sequence was developed. The reaction of phosphonium salt 3, arylglyoxals 4, amine 5 (or without), and isocyanide 6 produced the 2,3-di
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