Journal of Pharmaceutical Sciences p. 1854 - 1856 (1984)
Update date:2022-08-17
Topics:
McChesney
Sarangan
Hufford
Preparation of all possible monobromo-6-methoxy-8-aminoquinolines is reported. These materials provided an opportunity to assess the effect of bromine substitution on 13C-NMR chemical shift patterns. An explanation of the isomerization of 5-bromo-6-methoxy-8-acetamidoquinoline to 7-bromo-6-methoxy-8-aminoquinoline during hydrolysis is presented.
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