4-Amino-1,5-dihydro-2H-pyrrol-2-ones from boron trifluoride catalyzed reactions of 3-amino-2H-azirines with carboxylic acid derivatives

Article abstract of DOI:10.1002/hlca.19950780608

Reaction of 3-amino-2H-azirines 1 with ethyl 2-nitroacetate (6a) in refluxing MeCN affords 4-amino-1,5-dihydro-2H-pyrrol-2-ones 7 and 3,6-diamino-2,5-dihydropyrazines 8, the dimerization product of 1. Thus, 6a reacts with 1 as a CH-acidic compound by C-C