Phosphatosulfates. Metal-ion Effects on the Acid-catalyzed Hydrolysis of Phenyl Phosphatosulfate in an Acetonitrile-Water Mixed Solvent

Article abstract of DOI:10.1246/bcsj.55.1097

The rates of the acid-catalyzed hydrolysis of phenyl phosphatosulfate (PPS) have been found to be highly dependent on the water content in the mixed solvent of acetonitrile-water.A remarkable rate acceleration was observed with a rate maximum near the 1:1 ratio of PPS and metal ion, and with a solvent with a low water content.Under such conditions, the site of the cleavage of the P-O-S linkage was observed to be predominantly the S-O bond.