Rapid and efficient entry to substituted 2-succinimidobenzoate-3-azabicyclo[3.3.1]nonanes: AE-bicyclic analogues of methyllycaconitine

DOI: 10.1016/S0040-4039(00)78478-4

Source and publish data:

Tetrahedron Letters p. 8709 - 8712 (1994)

Update date:2022-08-17

Topics:

Authors:

Coates Coates

Coates, Philippa A.

Blagbrough

Blagbrough, Ian S.

Rowan Rowan

Rowan, Michael G.

Potter Potter

Potter, Barry V. L.

Pearson Pearson

Pearson, David P. J.

Lewis Lewis

Lewis, Terence

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Article abstract of DOI:10.1016/S0040-4039(00)78478-4

A double Mannich reaction allows a rapid and efficient entry to substituted 3-azabicyclo[3.3.1]nonane analogues of methyllycaconitine (MLA), a selective antagonist of certain mammalian and insect α-bungarotoxin-sensitive nicotinic acetylcholine receptors.

Full text of DOI:10.1016/S0040-4039(00)78478-4

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