Novel C-nucleoside analogs of 1,3-dioxolane: Synthesis of enantiomeric (2'R,4'S)- and (2'S,4'R)-2-[4-hydroxymethyl)-1,3-dioxolan-2-yl]-1,3-thiazol-4-carboxa mide

Article abstract of DOI:10.1016/0040-4039(95)00625-M

Novel C-nucleosides (2'R,4'S)-and (2'S,4'R)-2-[4-(hydroxymethyl)-1,3-dioxolan-2-yl]-1,3-thiazole-4-carbo xamide have been synthesized from stereoselectively induced condensation of optically active triols (S or R) with a 1,3-thiazole-4-carboxamide derivat