Tetrahedron p. 769 - 773 (1980)
Update date:2022-08-04
Topics:
Whitney, Richard R.
Jaeger, David A.
The effects of crown ethers (6 and 7) on the reactions of sodium (2a) and potassium enolates (2b) of 2-ethoxycarbonylcyclohexanone (1) with isopropyl iodide in dimethylsulfoxide and dimethoxyethane have been investigated. When the addition of crown ether promoted dissociation of ion pair 2 in either of the two solvents, the total rate of reaction (kt) increased and the ratio of carbon- (3) to oxygen-alkylation (4 and 5) products decreased. The results are consistent with the involvement of both the ion pair and more dissociated species in alkylation and with greater reactivity for the latter.
View MoreSHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.
website:http://www.tychemical.com
Contact:0086-358-3521713 3521715
Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Tianjin Chemsyntech Chemical Co., Ltd
Contact:+86-22-60872258
Address:Haitai green industry base in Tianjin, K1,5-601
Shanghai better-in Medical Technology Co.,LTD.
Contact:+86-21-38921049
Address:Lane 720 zhangjianggaoke cailun road, Pudong, Shanghai, room 513
HANGZHOU YUNUO CHEMICAL CO.,LTD
website:http://www.yunuochem.com
Contact:0571-83715115
Address:hangzhou
Hangzhou Deli Chemical Co.,Ltd.
website:http://www.dlchemical.com
Contact:86 571 28006267
Address:Tangxi Industrial Area, Yuhang District, Hangzhou
Doi:10.1002/ardp.19803130709
(1980)Doi:10.1139/v80-224
(1980)Doi:10.1021/ic034893i
(2004)Doi:10.1021/jo01314a032
(1980)Doi:10.1021/jo00315a041
(1981)Doi:10.1016/j.tet.2004.03.015
(2004)
