Studies on the reactivity of reductively activated mitomycin C

Article abstract of DOI:10.1021/ja00076a007

Mitomycin C (1a), a clinically significant antineoplastic antiobiotic, is considered to be the prototype of bioreductive alkylating agents. It has been reported that, in the absence of DNA, reductive activation of 1a furnished both solvolytic C(1) electro