Reactivity of Tricarbonyl(pentadienyl)iron(1+) Cations: Enantioselective Synthesis of 5-HETE Methyl Ester

Article abstract of DOI:10.1021/jo00060a033

The syntheses of racemic 5-HETE methyl ester (1) and of 5-HETE lactone (5-HL) were accomplished in 11 steps from tricarbonyl<1-(methoxycarbonyl)pentadienyl>iron(1+)hexafluorophosphate (2).A second synthesis of 1 from 2 in five steps was also achieved.Star