Journal of Medicinal Chemistry p. 1710 - 1715 (1983)
Update date:2022-08-10
Topics:
Angier, Robert B.
Citarella, Ronald V.
Damiani, Martin
Fabio, Paul F.
Fields, Thomas L.
et al.
A series of 3,6-bis(aminoalkoxy)acridines (2) was prepared and shown to have a protective antiviral effect against an interferon-sensitive virus (Columbia SK) and to partially restore an antibody response to a T-cell-dependent antigen in leukemic immunosuppressed mice.The presence of circulating interferon and the stimulation of natural killer cell activity in mice was observed for 21.
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