Stereospecificity of the Hydride Transfer Reaction Catalyzed by Isopropylmalate Dehydrogenase of Thermophilic Bacteria Thermus thermophilius

DOI: 10.1246/cl.1987.1749

Source and publish data:

Chemistry Letters p. 1749 - 1752 (1987)

Update date:2022-08-11

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Authors:

Yamada, Tohru

Kakinuma, Katsumi

Endo, Toyoshige

Oshima, Tairo

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Article abstract of DOI:10.1246/cl.1987.1749

Nuclear magnetic resonance studied on the NAD-dependent reaction catalyzed by isopropylmalate dehydrogenase from T. thermophilius HB8 revealed that pro R specific (A specific) hydride transfer from the substrate to the nicotinamide ring is involved during the said oxido-reduction.

Full text of DOI:10.1246/cl.1987.1749

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