Synthesis and in Vivo Antitumor Activity of Potential 5-Fluorouracil Prodrugs

DOI: 10.1021/jm00351a006

Source and publish data:

Journal of Medicinal Chemistry p. 1034 - 1040 (1982)

Update date:2022-08-12

Topics:

Authors:

Rosowsky, A.

Kim, S.-H.

Trites, D.

Wick, M.

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Article abstract of DOI:10.1021/jm00351a006

Analogues of 5'-deoxy-5-fluorouridine (DFUR, 1) were synthesized with the aim of evaluating the effect of structural modification of the 5' region of the ribofuranose moiety on the activity of these potential prodrug derivatives of 5-fluorouracil (FU).Rea

Full text of DOI:10.1021/jm00351a006

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