Tetrahedron Letters p. 1113 - 1116 (1998)
Update date:2022-08-11
Topics:
Hulme, Christopher
Morrissette, Matthew M.
Volz, Francis A.
Burns, Christopher J.
This communication describes the generation of high-yielding solution phase diketopiperazine libraries via a '3-step, 1-pot' procedure, employing the Ugi multi-component reaction (MCR), followed by BOC deprotection and cyclization to diketopiperazine (DKP). Exploitation of Armstrong's convertible isonitrile in the Ugi reaction utilising an 'internal nucleophile' approach for diketopiperazine formation is presented.
View More
shanghai jinshan pharmaceutical Co.,Ltd
Contact:021-57363011，13681638167
Address:No. 7966 Tingfeng Road,Jinshan,Shanghai,China
Chengdu Gelipu Biotechnology Co., Ltd.
website:http://www.glp-china.com
Contact:86-28-82610909
Address:chegndu
Contact:86-607-68073220
Address:1 ave na road jiahua st
Jewim Pharmaceutical (Shandong) Co., Ltd
Contact:+8615621883869
Address:山东省泰安市高新技术产业开发区配天门大街西首
Changsha Yihai Chemical Technology Co.,ltd
website:http://www.cs-yihai.com/
Contact:0731- 85620465
Address:Room 23005, unit 2, the northern building of Xiangsong international building , NO.259 Shaoshan Road , Changsha , Hunan, China.(mainland)
Doi:10.1002/cssc.201600348
(2016)Doi:10.1016/S0957-4166(03)00542-1
(2003)Doi:10.1016/j.phytochem.2019.112189
(2020)Doi:10.1016/j.tetlet.2016.03.062
(2016)Doi:10.1055/s-2003-41410
(2003)Doi:10.1039/J29660000726
(1966)
