Tetrahedron Letters p. 1113 - 1116 (1998)
Update date:2022-08-11
Topics:
Hulme, Christopher
Morrissette, Matthew M.
Volz, Francis A.
Burns, Christopher J.
This communication describes the generation of high-yielding solution phase diketopiperazine libraries via a '3-step, 1-pot' procedure, employing the Ugi multi-component reaction (MCR), followed by BOC deprotection and cyclization to diketopiperazine (DKP). Exploitation of Armstrong's convertible isonitrile in the Ugi reaction utilising an 'internal nucleophile' approach for diketopiperazine formation is presented.
View More
Changzhou Ansciep Chemical Co.,Ltd.
Contact:+86 519 8630 5871
Address:A-710 Boan International, 8 East Guangdian Road,Wujin,Changzhou
SHANGHAI RC CHEMICALS CO.,LTD.
website:http://www.rcc.net.cn
Contact:+86-21-50322175
Address:Rm1415 Yinqiao Masion No.58 Jinxin Road Pudong Shanghai China
Tianjin Emulsion Science&Technology Development Co.,Ltd
Contact:13901380442
Address:Vake Garden New Town New Yi Bai Road Beichen District Tianjin,China
Buffett (China) Holding Co.,Ltd
Contact:4006570891
Address:
Contact:+86-371-67759225
Address:No.32, Jinsuo Road, High-tech Zone
Doi:10.1002/cssc.201600348
(2016)Doi:10.1016/S0957-4166(03)00542-1
(2003)Doi:10.1016/j.phytochem.2019.112189
(2020)Doi:10.1016/j.tetlet.2016.03.062
(2016)Doi:10.1055/s-2003-41410
(2003)Doi:10.1039/J29660000726
(1966)
