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4. Conclusions
Lanthanide complexes of 2-benzoylpyridine benzhydra-
zone (BPBH) have been synthesized and characterized.
Physico-chemical and spectral studies reveal that the
complexes have general formula [Ln(BPBH)2(NO3)3]
(where Ln = La, Ce, Pr and Nd). BPBH acts as a neutral
tridentate ligand and NO3− acts as bidentate ligand. Two
BPBH ligands occupy six coordination sites and three
NO−3 ligands another six coordination sites to form 12-
coordinated mononuclear complexes. The structure of
[Ce(BPBH)2(NO3)3] complex was determined by single
crystal X-ray diffraction studies. Binding studies sug-
gest groove binding of the complexes with DNA. The
complexes show nuclease activity in the presences of
H2O2.
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KR is thankful to UGC, New Delhi for the award
Project Fellowship. The authors are thankful to UGC,
New Delhi [Sanction No. F 40-80/2011(SR)] for finan-
cial support. Authors are also thankful to SAIF, IIT- 18. Ganeshpandan M, Loganathan R, Suresh E, Rivasdeen
A, Akbarsha M A and Palanindavar M 2014 Dalton
Trans. 1203
Madras for providing X-ray crystallographic data. KHR
is thankful to UGC for the sanction of one-time finan-
cial grant [Sanction No. F.19-106/2013(BSR)]. The
authors also thank UGC and DST for providing equip-
ment facility under SAP and FIST programs.
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Supplementary Information
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Book Cancer Therapeutics Part II Experimental and
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1121
CCDC 917957 contains the supplementary crystal-
lographic data for Ce complex. These data can be
tallographic Data Centre, 12 Union Road, Cambridge
CB2 1EZ, UK; fax: +44 1223 336 033; or e-mail:
deposit@ccdc.cam.ac.uk. Figures S1 and S2 show the
electronic spectra of complexes. Tables S1 and S2 give
analytical and electronic spectral data respectively. Sup-
30. Preshagen E and Borbas E 2014 Coord. Chem. Rev. 273–
274 30
31. Dos santos C M G, Andrew J H, Susan J Q and
Gunnlaugsson T 2008 Coord. Chem. Rev. 252 2512
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