Synthesis and Properties of Chiral Macrobicyclic and Macrotricyclic Cryptands Containing the trans-Tetrahydrofuran-2,5-diylbis(methylene) Subunit as the Chiral Center

Article abstract of DOI:10.1246/bcsj.60.1789

The macrobicyclic and macrotricyclic cryptands containing the trans-tetrahydrofuran-2,5-diylbis(methylene) molecular framework as the chiral subunit were prepared in optically active forms.The enantiomer recognition property of the macrotricyclic tetracarboxamide (+)-6 in transport of enantiomeric molecules was examined, and the cation-binding abilities of the macrotricyclic and macrobicyclic amines 7, 10, and 13 were also investigated.