Reported in EPA TSCA Inventory.

DOT Classification:  8; Label: Corrosive

The Piperazine, with the CAS registry number 110-85-0, is also known as 1,4-Diazacyclohexane. It belongs to the product categories of Blocks; BuildingBlocks; Organics; Heterocycles; Isotope Labelled Compounds. Its EINECS number is 203-808-3. This chemical's molecular formula is C₄H₁₀N₂ and molecular weight is 86.13. What's more, its systematic name is Piperazine. Its classification codes are: (1) Agricultural Chemical; (2)Anthelmintic; (3)Anthelmintics; (4)Anti-Infective Agents; (5)Antinematodal agents; (6)Antiparasitic Agents; (7)Drug / Therapeutic Agent; (8)Human Data; (9)Skin / Eye Irritant; (10)Unspecified / Unclassified pesticide. This chemical should be sealed and stored in a cool, ventilated and dry place. Moreover, it should be protected from oxides, heat and fire. This chemical is commonly used as a pharmaceutical intermediate. It is also used in the manufacture of plastics, resins, pesticides, brake fluid and other industrial materials.

Physical properties of Piperazine are: (1)ACD/LogP: -1.171; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -4.41; (4)ACD/LogD (pH 7.4): -3.28; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 24.06 Å²; (13)Index of Refraction: 1.424; (14)Molar Refractivity: 25.143 cm³; (15)Molar Volume: 98.521 cm³; (16)Polarizability: 9.968×10^-24cm³; (17)Surface Tension: 27.6 dyne/cm; (18)Density: 0.874 g/cm³; (19)Flash Point: 49.726 °C; (20)Enthalpy of Vaporization: 38.624 kJ/mol; (21)Boiling Point: 149.324 °C at 760 mmHg; (22)Vapour Pressure: 4.0 mmHg at 25°C.

Uses of Piperazine: it can be used to produce 1-(3-methyl-butyl)-piperazine by heating. It will need reagent triethylamine and solvent ethanol with the reaction time of 17 hours. The yield is about 62%.

When you are using this chemical, please be cautious about it as the following:
This chemical can cause burns. It may cause sensitisation by inhalation and skin contact. This substance is harmful to aquatic organisms as it may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. You should not breathe dust. When using it, you need wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible). You should avoid releasing it to the environment, and you need refer to special instructions/safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: C1CNCCN1
(2)Std. InChI: InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2
(3)Std. InChIKey: GLUUGHFHXGJENI-UHFFFAOYSA-N

The toxicity data is as follows: