3-(4-Fluoro-phenyl)-3H-quinazolin-4-one

Base Information

Chemical Name:3-(4-Fluoro-phenyl)-3H-quinazolin-4-one
CAS No.:331983-26-7
Molecular Formula:C14H9FN2O
Molecular Weight:240.237
Hs Code.:
NSC Number:750359
DSSTox Substance ID:DTXSID60355083
Nikkaji Number:J1.917.577D
Wikidata:Q82133713

Synonyms:331983-26-7;3-(4-Fluoro-phenyl)-3H-quinazolin-4-one;3-(4-fluorophenyl)quinazolin-4(3H)-one;HMS1674H16;SCHEMBL16291434;DTXSID60355083;NSC750359;STK877473;AKOS000544820;NSC-750359;3-(4-fluorophenyl)-3,4-dihydroquinazolin-4-one;3-(4-fluorophenyl)quinazolin-4(3H)-one, AldrichCPR

Suppliers and Price of 3-(4-Fluoro-phenyl)-3H-quinazolin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 3-(4-Fluoro-phenyl)-3H-quinazolin-4-one

Chemical Property:

PSA：34.89000
LogP:2.52480
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:240.06989108
Heavy Atom Count:18
Complexity:350

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(=O)N(C=N2)C3=CC=C(C=C3)F

Technology Process of 3-(4-Fluoro-phenyl)-3H-quinazolin-4-one

There total 24 articles about 3-(4-Fluoro-phenyl)-3H-quinazolin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 201230-82-2
carbon monoxide

: 615-43-0
2-iodophenylamine

: 371-40-4
4-fluoroaniline

: 149-73-5
trimethyl orthoformate

: 331983-26-7
3-(4-fluorophenyl)quinazolin-4-(3H)-one

Guidance literature:: With palladium 10% on activated carbon; N-ethyl-N,N-diisopropylamine; In toluene; at 110 ℃; for 20h; under 7500.75 Torr; Autoclave;
DOI:10.1039/c5cy00907c

Reference yield: 96.0%

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 371-40-4
4-fluoroaniline

: 149-73-5
trimethyl orthoformate

: 331983-26-7
3-(4-fluorophenyl)quinazolin-4-(3H)-one

Guidance literature:: With lanthanum(III) nitrate; at 20 ℃; for 0.0833333h;
DOI:10.1016/j.tetlet.2006.04.096

Reference yield: 95.0%

: 4252-31-7
N-formylbenzamide

: 216502-06-6
2-amino-N-(4'-fluorophenyl)benzamide

: 331983-26-7
3-(4-fluorophenyl)quinazolin-4-(3H)-one

Guidance literature:: With pyridinium p-toluenesulfonate; In tetrahydrofuran; at 70 ℃; for 9h; Inert atmosphere; Green chemistry;
DOI:10.1039/d0ob01080d