Benzoic acid 2,2,2-trichloroethyl ester

Base Information

• Chemical Name: Benzoic acid 2,2,2-trichloroethyl ester
• CAS No.: 37934-99-9
• Molecular Formula: C9H7Cl3O2
• Molecular Weight: 253.512
• Hs Code.: 2916310090
• Mol file: 37934-99-9.mol

Synonyms:benzoic acid-(2,2,2-trichloro-ethyl ester);Benzoesaeure-(2,2,2-trichlor-aethylester);

Chemical Property of Benzoic acid 2,2,2-trichloroethyl ester

Chemical Property:

• PSA: 26.30000
• LogP: 3.21360

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid 2,2,2-trichloroethyl ester

There total 8 articles about Benzoic acid 2,2,2-trichloroethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzoic acid (65-85-0,8013-63-6) + 2,2,2-Trichloroethyl chloroformate (17341-93-4) → 2,2,2-trichloroethyl benzoate (37934-99-9)

Guidance literature:

With pentabutyl propyl guanidinium chloride; silica gel; at 120 ℃; for 3h;

DOI:10.1080/00397919308011284

Reference yield: 87.0%

1,1,1-trichloroethanol (115-20-8) + benzoyl chloride (98-88-4) → 2,2,2-trichloroethyl benzoate (37934-99-9)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 2.08333h;

DOI:10.1021/jo991711m

Reference yield: 61.0%

1,1,1-trichloroethanol (115-20-8) + benzaldehyde (100-52-7) → 2,2,2-trichloroethyl benzoate (37934-99-9)

Guidance literature:

With 4-ethyl-1-methyl-4H-[1,2,4]-triazol-1-ium iodide; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 45 ℃; for 24h; Solvent;

DOI:10.1039/c3cc42597e

upstream raw materials:

1,1,1-trichloroethanol

benzoyl chloride

benzoic acid

2,2,2-Trichloroethyl chloroformate

Downstream raw materials:

benzoic acid

2-methoxyethyl benzoate

N-benzylbenzamide

benzoic acid 2,2-dichloroethyl ester