Splitomicin

Base Information

Chemical Name:Splitomicin
CAS No.:5690-03-9
Molecular Formula:C13H10O2
Molecular Weight:198.21700
Hs Code.:2914399090
DSSTox Substance ID:DTXSID201017436
Nikkaji Number:J1.714.894J
Wikidata:Q27088853
Pharos Ligand ID:4CGURH71RALJ
ChEMBL ID:CHEMBL86537
Mol file:5690-03-9.mol

Synonyms:splitomicin

Suppliers and Price of Splitomicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Splitomicin
10mg
$ 403.00

Usbiological
Splitomicin
1mg
$ 269.00

TRC
Splitomycin
10mg
$ 90.00

TRC
Splitomycin
5mg
$ 55.00

TCI Chemical
Splitomicin >98.0%(GC)
1g
$ 471.00

TCI Chemical
Splitomicin >98.0%(GC)
200mg
$ 158.00

Sigma-Aldrich
Splitomicin ≥98% (HPLC), powder
5mg
$ 77.70

Medical Isotopes, Inc.
Splitomycin
25 mg
$ 710.00

DC Chemicals
Splitomicin >98%
250 mg
$ 500.00

CSNpharm
Splitomicin
250mg
$ 144.00

Total 17 raw suppliers

Chemical Property of Splitomicin

Chemical Property:

Vapor Pressure:4.35E-06mmHg at 25°C
Melting Point:73-74.5℃
Boiling Point:383.6oC at 760 mmHg
Flash Point:161.2oC
PSA：26.30000
Density:1.255g/cm3
LogP:2.69140
Storage Temp.:2-8°C
Solubility.:insoluble in H2O; ≥44.2 mg/mL in EtOH with ultrasonic; ≥9.05 mg/mL in DMSO
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:198.068079557
Heavy Atom Count:15
Complexity:261

Purity/Quality:

99%, ^*data from raw suppliers

Splitomicin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)OC2=C1C3=CC=CC=C3C=C2
Uses Splitomicin is a selective and potent inhibitor of Sir2 (silent information regulator 2), producing an inhibitory effect on neutrophils. Acts as an anti-inflammatory agent.

Technology Process of Splitomicin

There total 10 articles about Splitomicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 79-10-7
acrylic acid

: 135-19-3
β-naphthol

: 5690-03-9
splitomicin

Guidance literature:: With AMBERLIST; In toluene; for 24h; AMBERLIST Reflux;

Reference yield: 72.0%

: 3-methanesulfonyloxypropionic acid naphthalen-2-yl ester

: 5690-03-9
splitomicin

Guidance literature:: With gold(III) chloride; silver trifluoromethanesulfonate; In 1,2-dichloro-ethane; at 120 ℃; for 48h;
DOI:10.1021/ja046890q