N-(3-Methylphenyl)carbamic acid methyl ester

Base Information

• Chemical Name: N-(3-Methylphenyl)carbamic acid methyl ester
• CAS No.: 39076-18-1
• Molecular Formula: C9H11NO2
• Molecular Weight: 165.192
• Hs Code.: 2924299090
• Mol file: 39076-18-1.mol

Synonyms:

Chemical Property of N-(3-Methylphenyl)carbamic acid methyl ester

Chemical Property:

• Vapor Pressure: 0.232mmHg at 25°C
• Boiling Point: 206.8°Cat760mmHg
• Flash Point: 78.9°C
• PSA: 41.82000
• Density: 1.138g/cm³
• LogP: 2.18690

Purity/Quality:

99% ^*data from raw suppliers

METHYL-N-(META-TOLYL)CARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(3-Methylphenyl)carbamic acid methyl ester

There total 13 articles about N-(3-Methylphenyl)carbamic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methanol (67-56-1) + m-toluamide (618-47-3) → methyl N-(3-methylphenyl)carbamate (39076-18-1)

Guidance literature:

With sodium bromide; In acetonitrile; at 50 ℃; for 6h; Electrochemical reaction; Green chemistry;

DOI:10.1039/c8ob01059e

Reference yield: 90.0%

methyl chloroformate (79-22-1) + 1-amino-3-methylbenzene (108-44-1) → methyl N-(3-methylphenyl)carbamate (39076-18-1)

Guidance literature:

yttria-zirconia based Lewis acid catalyst; In acetonitrile; at 20 ℃; for 0.133333h;

DOI:10.1081/SCC-120026337

Reference yield: 87.0%

hydrazinecarboxylic acid methyl ester (6294-89-9) + 1-amino-3-methylbenzene (108-44-1) → methyl N-(3-methylphenyl)carbamate (39076-18-1)

Guidance literature:

With tert.-butylhydroperoxide; copper(ll) bromide; In water; acetonitrile; at 20 ℃; for 4h; Sealed tube; Schlenk technique;

DOI:10.1021/acs.joc.1c01031

upstream raw materials:

methanol

m-toluamide

carbon monoxide

1-methyl-3-nitrobenzene

Downstream raw materials:

Chloromethyl-m-tolyl-carbamic acid methyl ester