8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile

Base Information

Chemical Name:8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile
CAS No.:65619-92-3
Molecular Formula:C11H18N2O2
Molecular Weight:210.276
Hs Code.:
Mol file:65619-92-3.mol

Synonyms:4-cyano-4-dimethylaminocyclohexanone;8-dimethylamino-1,4-dioxa-spiro[4.5]decane-8-carbonitrile;8-cyano-[1,4-dioxaspiro[4.5]dec-8-yl]dimethylamine;

Suppliers and Price of 8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile
500mg
$ 1320.00

Medical Isotopes, Inc.
8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile
50 mg
$ 650.00

American Custom Chemicals Corporation
8-DIMETHYLAMINO-1,4-DIOXASPIRO[4.5]DECAN-8-CARBONITRILE 95.00%
5MG
$ 499.26

Total 5 raw suppliers

Chemical Property of 8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile

Chemical Property:

PSA：45.49000
LogP:1.12748
Solubility.:Dichloromethane, Ethyl Acetate

Purity/Quality:

99% ^*data from raw suppliers

8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 8-Dimethylamino-1,4-dioxaspiro[4.5]decan-8-carbonitrile is used in the preparation of a series of potent analgesics.

Technology Process of 8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile

There total 8 articles about 8-DiMethylaMino-1,4-dioxaspiro[4.5]decan-8-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: potassium cyanide

: 4746-97-8
cyclohexanedione monoethylene ketal

: 124-40-3
dimethyl amine

: 65619-92-3
8-(dimethylamino)-1,4-dioxaspiro-[4.5]-decane-8-carbonitrile

Guidance literature:: With hydrogenchloride; In methanol; water; at 20 ℃; for 72h; Cooling with ice;

Reference yield: 96.0%

: 4746-97-8
cyclohexanedione monoethylene ketal

: 151-50-8
potassium cyanide

: 124-40-3
dimethyl amine

: 65619-92-3
8-(dimethylamino)-1,4-dioxaspiro-[4.5]-decane-8-carbonitrile

Guidance literature:: With hydrogenchloride; In methanol; water; at 0 - 20 ℃; for 74h; Product distribution / selectivity;

Reference yield: 93.0%

: potassium cyanide

: 4746-97-8
cyclohexanedione monoethylene ketal

: 506-59-2
N,N-dimethylammonium chloride

: 124-40-3
dimethyl amine

: 65619-92-3
8-(dimethylamino)-1,4-dioxaspiro-[4.5]-decane-8-carbonitrile

Guidance literature:: cyclohexanedione monoethylene ketal; N,N-dimethylammonium chloride; In methanol; at 20 ℃; for 0.166667h; Inert atmosphere;

potassium cyanide; dimethyl amine; In methanol; water; at 20 ℃; for 48h; Inert atmosphere;