N-(6-chloropyridin-2-yl)acetamide

Base Information

Chemical Name:N-(6-chloropyridin-2-yl)acetamide
CAS No.:80364-46-1
Molecular Formula:C7H7ClN2O
Molecular Weight:170.598
Hs Code.:2933399990
DSSTox Substance ID:DTXSID70511951
Wikidata:Q82370998
Mol file:80364-46-1.mol

Synonyms:N-(6-chloropyridin-2-yl)acetamide;80364-46-1;Acetamide, N-(6-chloro-2-pyridinyl)-;SCHEMBL421678;DTXSID70511951;ZCLSYJAUDAXCGN-UHFFFAOYSA-N;MFCD11976374;N-(6-Chloro-2-pyridinyl)-acetamide;AKOS016667068;SB53868;F17978;A864701

Suppliers and Price of N-(6-chloropyridin-2-yl)acetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N-(6-Chloropyridin-2-yl)acetamide
50mg
$ 45.00

Labseeker
Acetamide,N-(6-chloro-2-pyridinyl)- 95
25g
$ 3208.00

Labseeker
Acetamide,N-(6-chloro-2-pyridinyl)- 95
10g
$ 2475.00

Labseeker
Acetamide,N-(6-chloro-2-pyridinyl)- 95
5g
$ 1833.00

Crysdot
N-(6-Chloropyridin-2-yl)acetamide 95+%
5g
$ 646.00

Crysdot
N-(6-Chloropyridin-2-yl)acetamide 95+%
10g
$ 1112.00

Chemenu
N-(6-Chloropyridin-2-yl)acetamide 95%
10g
$ 1040.00

Chemenu
N-(6-Chloropyridin-2-yl)acetamide 95%
5g
$ 604.00

Chemcia Scientific
N-(6-Chloro-pyridin-2-yl)-acetamide ＞97%
1 G
$ 140.00

Alichem
N-(6-Chloropyridin-2-yl)acetamide
10g
$ 1123.12

Total 12 raw suppliers

Chemical Property of N-(6-chloropyridin-2-yl)acetamide

Chemical Property:

PSA：45.48000
LogP:2.34290
XLogP3:1.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:170.0246905
Heavy Atom Count:11
Complexity:151

Purity/Quality:

97% ^*data from raw suppliers

N-(6-Chloropyridin-2-yl)acetamide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=NC(=CC=C1)Cl

Technology Process of N-(6-chloropyridin-2-yl)acetamide

There total 4 articles about N-(6-chloropyridin-2-yl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 45644-21-1
6-chloropyridin-2-amine

: 75-36-5
acetyl chloride

: 80364-46-1
N-(6-chloropyridin-2-yl)acetamide

Guidance literature:: With pyridine; In dichloromethane; at 0 - 5 ℃; for 1.33333h;
DOI:10.1021/acs.oprd.9b00556

Reference yield: 69.0%

: 20885-12-5
2-chloro-6-fluoropyridine

: 124-42-5
acetamidine hydrochloride

: 80364-46-1
N-(6-chloropyridin-2-yl)acetamide

Guidance literature:: With water; caesium carbonate; In dimethyl sulfoxide; at 90 ℃; for 18h; chemoselective reaction; Schlenk technique;
DOI:10.1039/d0ob01904f

Reference yield: 65.0%

: 60-35-5
acetamide

: 2402-78-0
2,6-dichloropyridine

: 80364-46-1
N-(6-chloropyridin-2-yl)acetamide

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; at 100 ℃; for 16h; Inert atmosphere; Sealed tube;