Tyr-gly-gly

Base Information

Chemical Name:Tyr-gly-gly
CAS No.:21778-69-8
Molecular Formula:C13H17N3O5
Molecular Weight:295.295
Hs Code.:2924299090
UNII:DS6B3J0V03
Nikkaji Number:J346.189K
Wikidata:Q27145057
NCI Thesaurus Code:C1132
Metabolomics Workbench ID:86403
ChEMBL ID:CHEMBL191422
Mol file:21778-69-8.mol

Synonyms:Imreg tripeptide;TGG tripeptide;Tyr-Gly-Gly;tyrosyl-glycyl-glycine;tyrosylglycylglycine;YGG tripeptide

Suppliers and Price of Tyr-gly-gly

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-2-(2-(2-Amino-3-(4-hydroxyphenyl)propanamido)acetamido)aceticacid 95+%
5g
$ 707.00

American Custom Chemicals Corporation
L-TYROSYLGLYCYGLYCINE 95.00%
100MG
$ 194.25

American Custom Chemicals Corporation
L-TYROSYLGLYCYGLYCINE 95.00%
500MG
$ 839.45

Alichem
(S)-2-(2-(2-Amino-3-(4-hydroxyphenyl)propanamido)acetamido)aceticacid
1g
$ 207.36

AK Scientific
Tyr-Gly-Gly
1g
$ 250.00

AK Scientific
Tyr-Gly-Gly
250mg
$ 120.00

AK Scientific
Tyr-Gly-Gly
100mg
$ 81.00

Total 22 raw suppliers

Chemical Property of Tyr-gly-gly

Chemical Property:

Appearance/Colour:White crystalline powder
Vapor Pressure:4.18E-23mmHg at 25°C
Melting Point:193-195℃
Refractive Index:1.6
Boiling Point:741.8 °C at 760 mmHg
Flash Point:402.4 °C
PSA：141.75000
Density:1.381 g/cm³
LogP:0.06110
Storage Temp.:−20°C
XLogP3:-3.5
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:295.11682065
Heavy Atom Count:21
Complexity:380

Purity/Quality:

98%min ^*data from raw suppliers

(S)-2-(2-(2-Amino-3-(4-hydroxyphenyl)propanamido)acetamido)aceticacid 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1CC(C(=O)NCC(=O)NCC(=O)O)N)O
Isomeric SMILES:C1=CC(=CC=C1C[C@@H](C(=O)NCC(=O)NCC(=O)O)N)O
Uses Tripeptide released from enkephalins by the enzyme enkephalinase.

Technology Process of Tyr-gly-gly

There total 13 articles about Tyr-gly-gly which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

: 1332726-69-8
methyl (S) [N-(tert-butoxycarbonyl)-O-tert-butyldimethylsilyl]tyrosylglycylglycinate

: 1332726-72-3
TBDMS-O-Boc-N-Tyr-Gly-Gly-OH

: 21778-69-8
tyrosylglycylglycine

: 59481-76-4
tert-butoxycarbonyl-L-tyrosyl-glycyl-glycine

Guidance literature:: With water; lithium hydroxide; In methanol; at 20 ℃; for 17h; Inert atmosphere;
DOI:10.1080/10426507.2010.535398

Reference yield: 34.0%

: tetrabutylphosphonium glycinate

: 3417-91-2
L-tyrosine methyl ester HCl

: 21778-69-8
tyrosylglycylglycine

Guidance literature:: tetrabutylphosphonium glycinate; for 3h; Inert atmosphere;

L-tyrosine methyl ester HCl; In chloroform; at 60 ℃; for 48h;

With acetic acid; In chloroform; at 20 ℃; for 3h;
DOI:10.1002/chem.201501783

Reference yield:

: 81678-16-2
leucine enkephalin acetate

: 63-91-2,25191-15-5,658-69-5,67675-33-6
L-phenylalanine

: 673-08-5
YG

: 3303-55-7
L-Phe-Leu

: 21778-69-8
tyrosylglycylglycine

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 60254-83-3
[des-tyr¹]-leucine enkephalin

Guidance literature:: In water; at 37 ℃; for 6h; Product distribution; Rate constant; enzymes: leucine aminopeptidase , carboxypeptidase B; degradation in extracts of various mucosae (nasal, rectal, vaginal); female White Albino rabbits; different inhibitors (amastatin, thimerosal, thiorphan); pH=5-8;
DOI:10.1002/jps.2600821124