1,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one

Base Information

• Chemical Name: 1,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one
• CAS No.: 13718-94-0
• Molecular Formula: C12H22O11
• Molecular Weight: 342.3
• Hs Code.: 29400090
• European Community (EC) Number: 237-282-1
• Mol file: 13718-94-0.mol

Synonyms:13718-94-0;143BB4C7-69C7-4F7B-9F75-CCA1022B6BB1

Chemical Property of 1,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one

Chemical Property:

• Appearance/Colour: White crystals
• Vapor Pressure: 1.14E-21mmHg at 25°C
• Melting Point: 125-128 °C
• Refractive Index: 99 ° (C=1, H2O)
• Boiling Point: 784.843 °C at 760 mmHg
• PKA: 11.85±0.20(Predicted)
• Flash Point: 292.547 °C
• PSA: 189.53000
• Density: 1.694 g/cm³
• LogP: -5.39560
• Storage Temp.: Refrigerator
• Solubility.: Methanol (Slightly), Water (Slightly, Heated, Sonicated)
• Water Solubility.: almost transparency
• XLogP3: -4.8
• Hydrogen Bond Donor Count: 8
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 8
• Exact Mass: 342.11621151
• Heavy Atom Count: 23
• Complexity: 378

Purity/Quality:

99% ^*data from raw suppliers

Palatinose ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20/21/22-37/38-41-48
• Safety Statements: 22-24/25-45-36/37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(C1C(C(C(C(O1)OCC(C(C(C(=O)CO)O)O)O)O)O)O)O
• Uses: Palatinose Hydrate is a natural occurring disaccharide composed of α-1,6-linked glucose and fructose and can be used as an alternative sugar. Because it is absorbed more slowly than sucrose it can be used as a sweetener for diabetic patients.

Technology Process of 1,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one

There total 12 articles about 1,3,4,5-Tetrahydroxy-6-[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.8%

Sucrose (57-50-1) → Isomaltulose (497-84-7,15132-06-6,58166-27-1,13718-94-0)

Guidance literature:

With sodium hydroxide; α-glucosyctransferase produced by Serratia; In water; at 30 - 50 ℃; for 50 - 60h; pH=6 - 7; Product distribution / selectivity; Enzymatic reaction;

Reference yield: 32.0%

Sucrose (57-50-1) → Isomaltulose (497-84-7,15132-06-6,58166-27-1,13718-94-0) + 1-O-α-D-Glucopyranosyl-D-fructose (90689-37-5)

Guidance literature:

In water; at 30 ℃; for 24h; biocatalyst from Protaminobacter rubrum (CBS 574.77);

DOI:10.1016/0008-6215(87)80152-0

Reference yield:

D-isomaltose (24822-33-1) → D-Fructose (57-48-7,18875-34-8) + α-D-glucopyranosyl-(1->6)-D-mannopyranose (197901-89-6) + Isomaltulose (497-84-7,15132-06-6,58166-27-1,13718-94-0) + D-Mannose (3458-28-4) + D-glucose (50-99-7)

Guidance literature:

With water; In ethanol; at 200 ℃; under 75007.5 Torr; Solvent; Kinetics; Supercritical conditions;

DOI:10.1080/09168451.2015.1127135

upstream raw materials:

Sucrose

levodopa

D-isomaltose

Downstream raw materials:

α-D-glucopyranosyl-(1->6)-D-gulitol

1-O-α-D-glucopyranosyl-D-mannitol

isomaltulose phenylosazone

5-hydroxymethyl-2-furfuraldehyde

Refernces

• 1、 Goerl, Julian,Timm, Malte,Seibel, Juergen. "Mechanism-Oriented Redesign of an Isomaltulose Synthase to an Isomelezitose Synthase by Site-Directed Mutagenesis". . p. 149 - 156. Retrieved 2012.
• 2、 -. "Microorganisms having enhanced sucrose mutase activity". Page/Page column. . Retrieved 2014/08/06.