3-(tert-Butylthio)propionic acid

Base Information

• Chemical Name: 3-(tert-Butylthio)propionic acid
• CAS No.: 927-91-3
• Molecular Formula: C7H14O2S
• Molecular Weight: 162.25000
• Hs Code.: 2930909090
• Mol file: 927-91-3.mol

Synonyms:3-tert.-Butylthio-propionsaeure;3-tert-Butylmercapto-propionsaeure;3-tert-butylsulfanyl-propionic acid;

Chemical Property of 3-(tert-Butylthio)propionic acid

Chemical Property:

• Boiling Point: 98-99 °C(Press: 1 Torr)
• PKA: 4.38±0.10(Predicted)
• PSA: 62.60000
• Density: 1.062±0.06 g/cm3(Predicted)
• LogP: 1.99280

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(tert-Butylthio)propionic acid

There total 5 articles about 3-(tert-Butylthio)propionic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.9%

3-mercaptopropionic acid (107-96-0) + tert-butyl alcohol (75-65-0) → 3-tert-butylsulfanyl-propionic acid (927-91-3)

Guidance literature:

With sulfuric acid; at 25 ℃; for 3h;

DOI:10.1080/10426500600614824

Reference yield:

3-Bromopropionic acid (590-92-1) + 2-methylpropan-2-thiol (75-66-1) → 3-tert-butylsulfanyl-propionic acid (927-91-3)

Guidance literature:

With sodium hydroxide; In ethanol;

DOI:10.1139/v65-008

Reference yield:

2-methylpropan-2-thiol (75-66-1) + acrylic acid (79-10-7) → 3-tert-butylsulfanyl-propionic acid (927-91-3)

Guidance literature:

With triethylamine;

DOI:10.1021/jo01030a060

upstream raw materials:

β-Propiolactone

2-methylpropan-2-thiol

methyl 3-(tert-butylthio)propanoate

3-Bromopropionic acid

Downstream raw materials:

5,5-Dimethyl-4-thiahexancarbonsaeure-t-butylester

3-tert-Butylmercapto-propionsaeure-anilid

(3-tert-butylsulfanyl-propionylamino)-acetic acid benzyl ester