Carbazole-9-ethanol

Base Information

• Chemical Name: Carbazole-9-ethanol
• CAS No.: 1484-14-6
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• Hs Code.: 2933990090
• European Community (EC) Number: 604-632-3
• NSC Number: 21081
• DSSTox Substance ID: DTXSID20281278
• Nikkaji Number: J1.037.136H
• Wikidata: Q72515198
• Mol file: 1484-14-6.mol

Synonyms:Carbazole-9-ethanol;1484-14-6;2-(9H-Carbazol-9-yl)ethanol;9H-Carbazole-9-ethanol;2-carbazol-9-ylethanol;9-(2-hydroxyethyl)carbazole;9H-Carbazole-ethanol;2-Carbazol-9-yl-ethanol;N-carbazolethanol;NSC21081;9H-carbazol-9-ethanol;2-(9-carbazolyl)ethanol;N-(2-hydroxyethyl)carbazole;Oprea1_073585;Oprea1_581102;N-(2-hydroxyethyl)-carbazole;SCHEMBL149177;9-(2-hydroxy ethyl)carbazole;AMY018;Ethanol, 2-(carbazol-9-yl)-;9H-Carbazole-9-ethanol, 95%;DTXSID20281278;2-(9H-Carbazol-9-yl)ethanol #;2-(CARBAZOL-9-YL)ETHANOL;BCP09115;MFCD00518704;NSC 21081;NSC-21081;STL575476;2,4-Difluoro-3-cyanophenylboronicacid;AKOS000629512;CS-W015050;AC-18964;AS-15094;FT-0633598;O10494;A808765;SR-01000517154;J-520001;SR-01000517154-1

Chemical Property of Carbazole-9-ethanol

Chemical Property:

• Appearance/Colour: Off-white fluffy crystalline powder
• Vapor Pressure: 1.27E-07mmHg at 25°C
• Melting Point: 78-82 °C(lit.)
• Refractive Index: 1.63
• Boiling Point: 414.7 °C at 760 mmHg
• PKA: 14.09±0.10(Predicted)
• Flash Point: 204.6 °C
• PSA: 25.16000
• Density: 1.17 g/cm³
• LogP: 2.78680
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 211.099714038
• Heavy Atom Count: 16
• Complexity: 221

Purity/Quality:

99% ^*data from raw suppliers

2-(9H-carbazol-9-yl)ethanol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2CCO
• Uses: 9H-Carbazole-9-ethanol may be used to synthesize 2-(9H-carbazol-9-yl)ethyl methacrylate.

Technology Process of Carbazole-9-ethanol

There total 19 articles about Carbazole-9-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) + 2-bromoethanol (540-51-2) → 2-carbazol-9-yl-ethanol (1484-14-6)

Guidance literature:

9H-carbazole; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; for 0.5h;

2-bromoethanol; In N,N-dimethyl-formamide; mineral oil; for 8h; Reflux;

Reference yield: 87.0%

9H-carbazole (86-74-8,105184-46-1,97960-57-1) + 2-chloro-ethanol (107-07-3) → 2-carbazol-9-yl-ethanol (1484-14-6)

Guidance literature:

9H-carbazole; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.333333h;

2-chloro-ethanol; In dimethyl sulfoxide; at 35 ℃; for 3h; Solvent; Sonication;

DOI:10.1002/jhet.1652

Reference yield: 83.0%

oxirane (75-21-8,99932-75-9) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 2-carbazol-9-yl-ethanol (1484-14-6)

Guidance literature:

With potassium hydroxide; In tetrahydrofuran; butanone; at -60 - 50 ℃; for 1h; Inert atmosphere; Microwave irradiation;

DOI:10.1016/j.ejmech.2013.09.038

upstream raw materials:

9H-carbazole

2-chloro-ethanol

cis,trans-2,5-dimethoxytetrahydrofuran

2-amino-ethanol hydrochloride

Downstream raw materials:

2-(9-carbazolyl)ethyl acrylate

N-(2-hydroxyethyl)carbazolyl methacrylate

2-(9H-carbazol-9-yl)ethyl 4-vinylbenzoate

C₂₁H₁₉NO₃S