1-Phenyl-2-(pyridin-3-yl)ethanone

Base Information

Chemical Name:1-Phenyl-2-(pyridin-3-yl)ethanone
CAS No.:1081-48-7
Molecular Formula:C13H11 N O
Molecular Weight:197.236
Hs Code.:
NSC Number:42664
DSSTox Substance ID:DTXSID60285710
Nikkaji Number:J621.518A
Wikidata:Q82021186
ChEMBL ID:CHEMBL57058
Mol file:1081-48-7.mol

Synonyms:1-phenyl-2-(pyridin-3-yl)ethanone;1081-48-7;1-phenyl-2-pyridin-3-ylethanone;1-Phenyl-2-(pyridin-3-yl)ethan-1-one;CHEMBL57058;NSC42664;alpha-3-Pyridylacetophenone;SCHEMBL1515767;DTXSID60285710;DDEBMFBOWGAMAX-UHFFFAOYSA-N;1-phenyl-2-(3-pyridinyl)ethanone;1-Phenyl-2-pyridin-3-yl-ethanone;1- Phenyl-2-(3-pyridyl)-ethanon;BDBM50028162;MFCD13689048;NSC-42664;1-Phenyl-2-(pyridine-3-yl)ethanone;AKOS011843153;1-PHENYL-2-(3-PYRIDYL)ETHANONE;F52957

Suppliers and Price of 1-Phenyl-2-(pyridin-3-yl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of 1-Phenyl-2-(pyridin-3-yl)ethanone

Chemical Property:

Vapor Pressure:4.93E-05mmHg at 25°C
Boiling Point:348.7°Cat760mmHg
Flash Point:172.6°C
Density:1.127g/cm³
XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:197.084063974
Heavy Atom Count:15
Complexity:209

Purity/Quality:: 98%,99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CC2=CN=CC=C2

Technology Process of 1-Phenyl-2-(pyridin-3-yl)ethanone

There total 21 articles about 1-Phenyl-2-(pyridin-3-yl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 626-60-8
3-Chloropyridine

: 308103-40-4
(2-acetylphenyl)boronic acid

: 1081-48-7
1-phenyl-2-(pyridin-3-yl)ethanone

Guidance literature:: 3-Chloropyridine; (2-acetylphenyl)boronic acid; With palladium diacetate; (R)-6-dicyclohexylphoshino-6'-diphenylphosphino-3,3'-dimethoxy-2,2',4,4'-tetramethyl-1,1'-biphenyl; In dodecane; butan-1-ol; at 25 ℃; for 0.0833333h; Glovebox; Inert atmosphere;

With cesiumhydroxide monohydrate; In dodecane; water; butan-1-ol; at 80 ℃; for 4h; Glovebox; Inert atmosphere;
DOI:10.1002/ejoc.201200918

Reference yield: 97.6%

: 1120-90-7
3-iodopyridine

: 98-86-2
acetophenone

: 1081-48-7
1-phenyl-2-(pyridin-3-yl)ethanone

Guidance literature:: acetophenone; With (2-dicyclohexylphosphino-2′,4′,6′-triisopropyl-1,1′-biphenyl)[2-(2′-N-methylamino-1,1′-biphenyl)]palladium(II) methanesulfonate; sodium t-butanolate; In toluene; at 20 ℃; for 0.166667h; Microwave irradiation;

3-iodopyridine; In toluene; at 130 ℃; for 0.166667h; Reagent/catalyst; Sealed tube; Microwave irradiation;
DOI:10.1021/acs.joc.9b00446

Reference yield: 94.0%

: 626-60-8
3-Chloropyridine

: 98-86-2
acetophenone

: 1081-48-7
1-phenyl-2-(pyridin-3-yl)ethanone

Guidance literature:: With C₄₆H₆₄ClPPd; potassium tert-butylate; In tetrahydrofuran; methanol; at 60 ℃; for 1h; Inert atmosphere;
DOI:10.1021/acscatal.5b00878