2-BROMOETHYL ETHYL SULFIDE

Base Information

• Chemical Name: 2-BROMOETHYL ETHYL SULFIDE
• CAS No.: 35420-95-2
• Molecular Formula: C4H9BrS
• Molecular Weight: 169.085
• Hs Code.: 2930909090
• Mol file: 35420-95-2.mol

Synonyms:Sulfide,2-bromoethyl ethyl (6CI);1-Bromo-2-(ethylthio)ethane;1-Bromo-2-ethylsulfanylethane;2-Bromoethyl ethyl sulfide;2-Ethylthioethylbromide;NSC 57104;b-Bromoethyl ethyl sulfide;w-Bromodiethyl sulfide;

Chemical Property of 2-BROMOETHYL ETHYL SULFIDE

Chemical Property:

• Vapor Pressure: 1.31mmHg at 25°C
• Refractive Index: 1.508
• Boiling Point: 178.9 °C at 760 mmHg
• Flash Point: 62 °C
• PSA: 25.30000
• Density: 1.389g/cm³
• LogP: 2.13440

Purity/Quality:

98%min ^*data from raw suppliers

1-bromo-2-(ethylsulfanyl)ethane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-BROMOETHYL ETHYL SULFIDE

There total 7 articles about 2-BROMOETHYL ETHYL SULFIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

2-(ethylsulfanyl)ethanol (110-77-0) → 1-bromo-2-(ethylsulphanyl)ethane (35420-95-2)

Guidance literature:

With phosphorus tribromide; In dichloromethane; at 0 ℃; for 2.33h; Inert atmosphere;

DOI:10.1021/ja4039505

Reference yield:

N,O-Bis(trimethylsilyl)trifluoroacetamide (25561-30-2) + 2-Chloroethyl ethyl sulfide (693-07-2) → 1,2-diethylthioethane (1633-90-5) + 1-bromo-2-(ethylsulphanyl)ethane (35420-95-2) + trimethyl-(2-vinylmercapto-ethoxy)-silane (18269-57-3) + (2-ethylthio)ethylene butyl ether + C7H18OSSi (959080-54-7) + vinyl ethylsulfide (627-50-9)

Guidance literature:

2-Chloroethyl ethyl sulfide; With cetyltrimethylammonim bromide; In hexane; water; butan-1-ol; at 25 ℃; for 0.5h;

N,O-Bis(trimethylsilyl)trifluoroacetamide; With sodium hydroxide; In acetonitrile; at 70 ℃; for 0.5h; pH=10; Mechanism;

DOI:10.1080/10426507.2013.820728

Reference yield:

ethylene dibromide (106-93-4) + ethanethiol (75-08-1) → 1-bromo-2-(ethylsulphanyl)ethane (35420-95-2)

Guidance literature:

ethanethiol; With sodium ethanolate; In ethanol; at 20 ℃; for 0.5h;

ethylene dibromide; In ethanol; at 0 - 20 ℃; for 1h;

DOI:10.1039/c6gc03187k

upstream raw materials:

2-(ethylsulfanyl)ethanol

ethanethiol

ethene

phosphorus tribromide

Downstream raw materials:

(2-ethylsulfanyl-ethyl)-phenyl-arsinic acid

S-ethyl-S-(2-bromo-ethyl)-N-(toluene-4-sulfonyl)-sulfimide

Demeton-S

C₂₈H₄₅N₆O₁₀PS

Refernces

• 1、 -. "METHOD OF TREATING CANCER WITH A COMBINATION OF BENZYLIDENEGUANIDINE DERIVATIVES AND CHEMOTHERAPEUTIC AGENT.". Page/Page column 60-61. . Retrieved 2017/03/08.
• 2、 -. "O-ALKYL-BENZYLIDENEGUANIDINE DERIVATIVES AND THERAPEUTIC USE FOR THE TREATMENT OF DISORDERS ASSOCIATED AN ACCUMULATION OF MISFOLDED PROTEINS". Page/Page column 74. . Retrieved 2016/01/25.