Troxerutin

Base Information Edit

Chemical Name:Troxerutin
CAS No.:7085-55-4
Deprecated CAS:12041-99-5,68244-17-7,27321-15-9,29702-52-1,37396-63-7,96304-71-1,1260230-02-1,288306-51-4
Molecular Formula:C33H42O19
Molecular Weight:742.685
Hs Code.:2932999099
European Community (EC) Number:230-389-4
UNII:7Y4N11PXO8
DSSTox Substance ID:DTXSID4045929
Nikkaji Number:J9.645H
Wikipedia:Troxerutin
Wikidata:Q72515635
NCI Thesaurus Code:C66645
Metabolomics Workbench ID:38818
ChEMBL ID:CHEMBL3182320
Mol file:7085-55-4.mol

Synonyms:3',4',7-trihydroxyethylrutin;3',4',7-tris(O-(2- hydroxyethyl))rutin;oxerutin;Paroven;Posorutin;Relvene;Rhéoflux;Teboven;Troxérutine Mazal;troxerutin;Troxerutin-ratiopharm;Troxeven;Vastribil;Veinamitol;Veniten retard;Veno SL;Venorutin;venoruton;venoruton P4;Venotrulan Trox;vitamin P4

Suppliers and Price of Troxerutin

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Troxerutin
50g
$ 425.00

Usbiological
Troxerutin
20mg
$ 305.00

TRC
Troxerutin(85%)
500mg
$ 65.00

TCI Chemical
Troxerutin >90.0%(HPLC)
25g
$ 49.00

TCI Chemical
Troxerutin >90.0%(HPLC)
5g
$ 17.00

Sigma-Aldrich
Troxerutin European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Troxerutin European Pharmacopoeia (EP) Reference Standard
y0000497
$ 190.00

Medical Isotopes, Inc.
Troxerutin
50 mg
$ 860.00

DC Chemicals
Troxerutin >98%,StandardReferencesGrade
20 mg
$ 280.00

CSNpharm
Troxerutin
50mg
$ 40.00

Total 198 raw suppliers

Chemical Property of Troxerutin Edit

Chemical Property:

Appearance/Colour:yellow powder
Vapor Pressure:0mmHg at 25°C
Melting Point:181 °C
Refractive Index:1.689
Boiling Point:1058.4 °C at 760 mmHg
PKA:5.92±0.40(Predicted)
Flash Point:332 °C
PSA：297.12000
Density:1.65 g/cm³
LogP:-2.69060
Storage Temp.:Refrigerator
Solubility.:Freely soluble in water, slightly soluble in ethanol (96 per cent) and practically insoluble in methylene chloride.
XLogP3:-2.4
Hydrogen Bond Donor Count:10
Hydrogen Bond Acceptor Count:19
Rotatable Bond Count:15
Exact Mass:742.23202911
Heavy Atom Count:52
Complexity:1170

Purity/Quality:

99%, ^*data from raw suppliers

Troxerutin ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O
Isomeric SMILES:C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=C(OC4=CC(=CC(=C4C3=O)O)OCCO)C5=CC(=C(C=C5)OCCO)OCCO)O)O)O)O)O)O
Uses Used in the treatment of venous disorders vasoprotectant Troxerutin, a derivative of the naturally occurring bioflavonoid rutin, is thought to inhibit red cell and platelet aggregation, improve erythrocyte deformability, and improve plasma viscosity retinal microcirculation. A double-blind randomized clinical trial compared troxerutin with placebo in 27 patients with CRVO. The limitations of the study included a small number of patients and short follow-up time.

Technology Process of Troxerutin

There total 6 articles about Troxerutin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%