7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Base Information

Chemical Name:7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one
CAS No.:36519-16-1
Molecular Formula:C9H11N5O5
Molecular Weight:269.2141
Hs Code.:
Mol file:36519-16-1.mol

Synonyms:

Suppliers and Price of 7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 4 raw suppliers

Chemical Property of 7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Chemical Property:

Vapor Pressure:1.34E-21mmHg at 25°C
Boiling Point:717.4°C at 760 mmHg
Flash Point:387.7°C
Density:2.29g/cm³

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

There total 9 articles about 7-pentofuranosyl-1,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 1643356-28-8
7-((2R,3R,4R,5R)-3,4-bis((tert-butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

: 36519-16-1
7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;
DOI:10.1039/c4ob00705k

Reference yield:

: 2627-69-2
AICA riboside

: 36519-16-1
7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Guidance literature:: With hydrogenchloride; sodium nitrite; In ethanol; water; at -30 ℃; for 2h;

Reference yield:

: 58-63-9
inosine

: 36519-16-1
7-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3,7-dihydro-4H-imidazo[4,5-d][1,2,3]triazin-4-one

Guidance literature:: Multi-step reaction with 7 steps

1: 1H-imidazole; tert-butyldimethylsilyl chloride / N,N-dimethyl-formamide / 48 h / 20 - 60 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 48 h / 20 - 60 °C / Inert atmosphere

3: ethylenediamine / tetrahydrofuran / 3 h / 20 - 50 °C / Inert atmosphere

4: ammonium fluoride / water; N,N-dimethyl-formamide / 24 h / 20 °C

5: sodium nitrite; hydrogenchloride / water; acetonitrile / 1 h / 0 °C

6: ethylenediamine / N,N-dimethyl-formamide / 2 h / 20 - 60 °C

7: tetrabutyl ammonium fluoride / tetrahydrofuran / 2 h / 0 °C / Inert atmosphere

With 1H-imidazole; hydrogenchloride; ammonium fluoride; tetrabutyl ammonium fluoride; potassium carbonate; tert-butyldimethylsilyl chloride; ethylenediamine; sodium nitrite; In tetrahydrofuran; water; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1039/c4ob00705k