Ethanol, 2-(1-naphthalenyloxy)-

Base Information

• Chemical Name: Ethanol, 2-(1-naphthalenyloxy)-
• CAS No.: 711-82-0
• Molecular Formula: C12H12O2
• Molecular Weight: 188.226
• Hs Code.: 2909499000
• DSSTox Substance ID: DTXSID9061045
• Nikkaji Number: J421.524I
• Wikidata: Q81989278
• Mol file: 711-82-0.mol

Synonyms:711-82-0;2-(Naphthalen-1-yloxy)ethanol;2-(1-naphthyloxy)ethanol;Ethanol, 2-(1-naphthalenyloxy)-;2-naphthalen-1-yloxyethanol;2-(naphthalen-1-yloxy)ethan-1-ol;2-(1-Naphthalenyloxy)ethanol;beta-Naphthoxyathanol;beta-naphthoxy-ethanol;2-(1-naphthyloxy)-1-ethanol;SCHEMBL1023529;DTXSID9061045;MFCD00080582;AKOS006031654;AS-16841;CS-0196154;FT-0651094;E89386

Chemical Property of Ethanol, 2-(1-naphthalenyloxy)-

Chemical Property:

• Vapor Pressure: 1.16E-05mmHg at 25°C
• Melting Point: 45 °C
• Refractive Index: 1.622
• Boiling Point: 355.2 °C at 760 mmHg
• Flash Point: 168.8 °C
• PSA: 29.46000
• Density: 1.164 g/cm³
• LogP: 2.21090
• Storage Temp.: 2-8°C
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 188.083729621
• Heavy Atom Count: 14
• Complexity: 170

Purity/Quality:

98%Min ^*data from raw suppliers

2-(Naphthalen-1-yloxy)ethanol 98% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2OCCO

Technology Process of Ethanol, 2-(1-naphthalenyloxy)-

There total 11 articles about Ethanol, 2-(1-naphthalenyloxy)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-Bromonaphthalene (90-11-9) + ethylene glycol (107-21-1) → 2-(1-naphthyloxy)-1-ethanol (711-82-0)

Guidance literature:

With potassium carbonate; copper dichloride; at 130 ℃; for 20h; Inert atmosphere; Schlenk technique;

DOI:10.1039/c4ob00649f

Reference yield: 94.0%

[1,3]-dioxolan-2-one (96-49-1) + α-naphthol (90-15-3) → 2-(1-naphthyloxy)-1-ethanol (711-82-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl acetamide; at 110 ℃; for 2h; Inert atmosphere;

Reference yield: 90.0%

α-naphthol (90-15-3) + 2-chloro-ethanol (107-07-3) → 2-(1-naphthyloxy)-1-ethanol (711-82-0)

Guidance literature:

With potassium carbonate; potassium iodide; In N,N-dimethyl-formamide; at 110 ℃; for 10h;

DOI:10.1002/asia.201701044

upstream raw materials:

oxirane

α-naphthol

2-chloro-ethanol

2-bromoethanol

Downstream raw materials:

2-(naphthalen-1-yloxy)ethyl chloride

α-naphthol

ethyl 1-(4-methoxybenzyl)-3-(2-(naphthalen-1-yloxy)ethoxy)-1H-indole-2-carboxylate

Refernces

• 1、 Wang, Ming,Li, Zhuang,Li, Hua,He, Jinghui,Li, Najun,Xu, Qingfeng,Lu, Jianmei. "Different Steric-Twist-Induced Ternary Memory Characteristics in Nonconjugated Copolymers with Pendant Naphthalene and 1,8-Naphthalimide Moieties". supporting information. p. 2744 - 2748. Retrieved 2017/10/07.
• 2、 -. "Indane derivative and synthetic method and medicinal application thereof". Paragraph 0056; 0057; 0058. . Retrieved 2017/09/02.