Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)-

Base Information

Chemical Name:Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)-
CAS No.:112904-69-5
Molecular Formula:C13H16O5
Molecular Weight:252.267
Hs Code.:

Synonyms:

Suppliers and Price of Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)-

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)-

Chemical Property:

Purity/Quality:

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Technology Process of Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)-

There total 11 articles about Pentanedioic acid, 3-(phenylmethoxy)-, monomethyl ester, (R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 67-56-1
methanol

: 838906-36-8
meso-4-(benzyloxy)glutaric anhydride

: 112904-69-5
(R)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid

Guidance literature:: With C₄₄H₄₅F₆N₃O₅S; In tert-butyl methyl ether; at 20 ℃; for 168h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/jo402829b

Reference yield:

: 67-56-1
methanol

: 838906-36-8
meso-4-(benzyloxy)glutaric anhydride

: 112904-69-5
(R)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid

: 117365-69-2
(S)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid

Guidance literature:: With C₄₄H₄₅F₆N₃O₅S; In tert-butyl methyl ether; at 20 ℃; for 168h; Solvent; Concentration; Time; Reagent/catalyst; Overall yield = 92 %; enantioselective reaction; Inert atmosphere;
DOI:10.1021/jo402829b

Reference yield:

: 112904-65-1
dimethyl 3-(benzyloxy)pentanedioate

: 112904-69-5
(R)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid

: 117365-69-2
(S)-3-(benzyloxy)-5-methoxy-5-oxopentanoic acid

Guidance literature:: With sodium hydroxide; α-chymotrypsin; In 1,4-dioxane; water; at 23 ℃; Product distribution; pH=7.8 Na₂HPO₄ buffer; variation of pH and enzyme;
DOI:10.1016/S0040-4039(00)96663-2