Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)-

Base Information

• Chemical Name: Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)-
• CAS No.: 113160-01-3
• Molecular Formula: C16H18O2
• Molecular Weight: 242.318
• DSSTox Substance ID: DTXSID80473591
• Nikkaji Number: J271.284I
• Mol file: 113160-01-3.mol

Synonyms:113160-01-3;Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)-;DTXSID80473591

Chemical Property of Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)-

Chemical Property:

• XLogP3: 3.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 242.130679813
• Heavy Atom Count: 18
• Complexity: 215

Purity/Quality:

99.90% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C(CC2=CC=CC=C2)OC

Technology Process of Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)-

There total 10 articles about Benzene, 1-methoxy-4-(1-methoxy-2-phenylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

1-(4-methoxyphenyl)-2-phenylethan-1-ol (5422-47-9) + methyl iodide (74-88-4) → 1-[2-methoxy-2-(4-methoxyphenyl)ethyl]benzene (113160-01-3)

Guidance literature:

With potassium hydroxide; for 0.5h;

DOI:10.1021/jo00242a030

Reference yield: 64.0%

methanol (67-56-1) + 4-Methoxystyrene (637-69-4,24936-44-5) + benzenediazonium tetrafluoroborate (369-57-3) → 1-[2-methoxy-2-(4-methoxyphenyl)ethyl]benzene (113160-01-3)

Guidance literature:

With 9-N-methylamino-1-oxophenalene; potassium tert-butylate; In dimethyl sulfoxide; at 25 ℃; for 24h; Reagent/catalyst; Solvent; Kinetics; Inert atmosphere; Glovebox;

DOI:10.1021/acs.joc.9b01744

Reference yield: 50.0%

methanol (67-56-1) + 4-Methoxystyrene (637-69-4,24936-44-5) + diphenyliodonium tetrafluoroborate → 1-[2-methoxy-2-(4-methoxyphenyl)ethyl]benzene (113160-01-3)

Guidance literature:

With tris[2-phenylpyridinato-C₂,N]iridium(III); zinc diacetate; at 20 ℃; for 18h; Sealed tube; Inert atmosphere; Irradiation;

DOI:10.1021/ol401940c

upstream raw materials:

methanol

E-1-(phenyl)-2-(4'-methoxyphenyl)ethene

phenylmagnesium bromide

4-methoxy-benzaldehyde