Diethyl 4-ethoxy-2,6-pyridinedicarboxylate

Base Information

Chemical Name:Diethyl 4-ethoxy-2,6-pyridinedicarboxylate
CAS No.:18986-18-0
Molecular Formula:C₁₃H₁₇NO₅
Molecular Weight:267.282
Hs Code.:2933399090
Mol file:18986-18-0.mol

Synonyms:4-ethoxy-pyridine-2,6-dicarboxylic acid diethyl ester;diethyl 4-ethoxy-2,6-pyridinedicarboxylate;4-Ethoxy-pyridin-2,6-dicarbonsaeurediethylester;4-ethoxy-2,6-pyridinedicarboxylate d'ethyle;4-Ethoxy-dipicolinsaeure-diethylester;4-Aethoxy-pyridin-2,6-dicarbonsaeure-diaethylester;

Suppliers and Price of Diethyl 4-ethoxy-2,6-pyridinedicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
DIETHYL-4-ETHOXY-2,6-PYRIDINEDICARBOXYLATE 95.00%
5MG
$ 505.49

AK Scientific
Diethyl4-ethoxypyridine-2,6-dicarboxylate
1g
$ 1518.00

Total 3 raw suppliers

Chemical Property of Diethyl 4-ethoxy-2,6-pyridinedicarboxylate

Chemical Property:

Vapor Pressure:1.62E-06mmHg at 25°C
Boiling Point:397.1oC at 760 mmHg
Flash Point:194oC
PSA：74.72000
Density:1.152g/cm3
LogP:1.83370

Purity/Quality:

99% ^*data from raw suppliers

DIETHYL-4-ETHOXY-2,6-PYRIDINEDICARBOXYLATE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Diethyl 4-ethoxy-2,6-pyridinedicarboxylate

There total 7 articles about Diethyl 4-ethoxy-2,6-pyridinedicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

: 74-96-4
ethyl bromide

: 68631-52-7
4-hydroxypyridine-2,6-dicarboxylic acid diethylester

: 18986-18-0
4-ethoxy-2,6-pyridinedicarboxylate d'ethyle

Guidance literature:: With potassium carbonate; In butanone;
DOI:10.1016/S0040-4020(03)00753-1

Reference yield:

: 53389-01-8
diethyl 4-chloropyridine-2,6-dicarboxylate

: 18986-18-0
4-ethoxy-2,6-pyridinedicarboxylate d'ethyle

Guidance literature:: With ethanol; sodium ethanolate;
DOI:10.1021/ja01597a074

Reference yield:

: 71022-75-8
4-chloropyridine-2,6-dicarbonyl dichloride

: 18986-18-0
4-ethoxy-2,6-pyridinedicarboxylate d'ethyle

Guidance literature:: Multi-step reaction with 2 steps

1: 52 percent / CH₂Cl₂ / 2 h / Heating

2: 1) NaH, 2) crown ether (18-c-6) / 1) THF, room temp., 1 h, 2) THF, reflux, 1 h

With 18-crown-6 ether; sodium hydride; In dichloromethane;