2-Iodo-4-methoxy-1-methylbenzene

Base Information

Chemical Name:2-Iodo-4-methoxy-1-methylbenzene
CAS No.:260558-14-3
Molecular Formula:C8H9IO
Molecular Weight:248.063
Hs Code.:
DSSTox Substance ID:DTXSID30572826
Nikkaji Number:J1.231.088I
Wikidata:Q82461319
Mol file:260558-14-3.mol

Synonyms:2-iodo-4-methoxy-1-methylbenzene;260558-14-3;Benzene, 2-iodo-4-methoxy-1-methyl-;SCHEMBL3459253;DTXSID30572826;MIHFMTLIZXCMMH-UHFFFAOYSA-N

Suppliers and Price of 2-Iodo-4-methoxy-1-methylbenzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemcia Scientific
2-Iodo-4-methoxy-1-methyl-benzene 95%
5 G
$ 1385.00

Alichem
3-Iodo-4-methylanisole
1g
$ 1460.20

Alichem
3-Iodo-4-methylanisole
500mg
$ 855.75

Total 3 raw suppliers

Chemical Property of 2-Iodo-4-methoxy-1-methylbenzene

Chemical Property:

PSA：9.23000
LogP:2.60820
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:247.96981
Heavy Atom Count:10
Complexity:105

Purity/Quality:

95% ^*data from raw suppliers

2-Iodo-4-methoxy-1-methyl-benzene 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C=C(C=C1)OC)I

Technology Process of 2-Iodo-4-methoxy-1-methylbenzene

There total 6 articles about 2-Iodo-4-methoxy-1-methylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 50868-72-9
5-methoxy-o-toluidine

: 260558-14-3
3-iodo-4-methylanisole

Guidance literature:: 5-methoxy-o-toluidine; With sulfuric acid; In water; at 0 ℃;

With sodium nitrite; In water; at 0 - 5 ℃;

With potassium iodide; In water; at 20 - 100 ℃; for 2h; Further stages.;
DOI:10.1002/ejoc.200700381

Reference yield: 63.0%

: 104-93-8
p-methylanizole

: 260558-14-3
3-iodo-4-methylanisole

: 50597-88-1
2-iodo-4-methylanisole

Guidance literature:: With iodine; dinitrogen tetraoxide; pyrographite; ferric nitrate; In dichloromethane; at 20 ℃; for 7h;
DOI:10.1016/j.tetlet.2003.09.189

Reference yield:

: 17484-36-5
4-Methyl-3-nitroanisole

: 260558-14-3
3-iodo-4-methylanisole

Guidance literature:: Multi-step reaction with 2 steps

1.1: hydrazine hydrate / palladium 10% on activated carbon / 1,2-dimethoxyethane / 52 h / Inert atmosphere; Reflux

2.1: nitrosonium tetrafluoroborate / acetonitrile / -20 - 0 °C

2.2: Cooling with ice

With nitrosonium tetrafluoroborate; hydrazine hydrate; palladium 10% on activated carbon; In 1,2-dimethoxyethane; acetonitrile;