D-Threitol

Base Information

• Chemical Name: D-Threitol
• CAS No.: 7493-90-5
• Molecular Formula: C₄H₁₀O₄
• Molecular Weight: 122.121
• European Community (EC) Number: 621-282-7,626-535-5
• UNII: 6DN82XBT5M
• DSSTox Substance ID: DTXSID801016717,DTXSID801336604
• Nikkaji Number: J7.872G
• Wikipedia: Threitol
• Wikidata: Q415347
• Metabolomics Workbench ID: 38475
• Mol file: 7493-90-5.mol

Synonyms:threitol;threitol, ((R*,R*)-(+-))-isomer;threitol, (R-(R*,R*))-isomer

Chemical Property of D-Threitol

Chemical Property:

• PSA: 80.92000
• LogP: -2.30720
• Storage Temp.: -20°C
• Solubility.: water: soluble50mg/mL, clear to slightly hazy, colorless to fain
• XLogP3: -2.3
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 122.05790880
• Heavy Atom Count: 8
• Complexity: 48

Purity/Quality:

98%,99%, ^*data from raw suppliers

DL-Threitol 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Classes -> Alcohols and Polyols, Other
• Canonical SMILES: C(C(C(CO)O)O)O
• Isomeric SMILES: C([C@H]([C@@H](CO)O)O)O

Technology Process of D-Threitol

There total 27 articles about D-Threitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

cis-2,3-epoxy-1,4-butanediol (4440-87-3,63621-92-1) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6)

Guidance literature:

With water; at 100 ℃; for 9h;

DOI:10.1021/jo702401t

Reference yield: 60.0%

1,4-butenediol (821-11-4,6117-80-2,110-64-5) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6)

Guidance literature:

With potassium permanganate; dihydrogen peroxide; In water; acetone; at 0 ℃; for 2h; Temperature; Inert atmosphere; Green chemistry;

DOI:10.1039/c5ra01646k

Reference yield: 53.6%

cellulose (9004-34-6) → 1,2,3,4-butanetetrol (2319-57-5,2418-52-2,6968-16-7,7493-90-5,7541-59-5,10030-58-7,188346-77-2,149-32-6) + ethylene glycol (107-21-1)

Guidance literature:

With ruthenium-carbon composite; hydrogen; In water; at 215 ℃; for 1.5h; under 39003.9 Torr; Reagent/catalyst; Catalytic behavior; Autoclave;

DOI:10.1039/c6ra27524a

upstream raw materials:

1,4-dibromo-2-butene

D-erythrose

buta-1,3-diene

formaldehyd

Downstream raw materials:

2,2'-diethyl-tetrahydro-[4,4']bi[1,3,2]dioxaborolyl

thiophene

(+/-)-erythronic acid

oxalic acid

Refernces

• 1、 Gumina, Bianca,Mauriello, Francesco,Pietropaolo, Rosario,Galvagno, Signorino,Espro, Claudia. "Hydrogenolysis of sorbitol into valuable C3-C2 alcohols at low H2 pressure promoted by the heterogeneous Pd/Fe3O4 catalyst". . p. 152 - 160. Retrieved 2018/02/17.
• 2、 Dalmizrak, Di?dem,G?ksu, Haydar,Gültekin, Mehmet Serdar. "A facile synthesis of vicinal cis-diols from olefins catalyzed by in situ generated MnxOy nanoaggregates". . p. 20751 - 20755. Retrieved 2015/03/18.