Methyl p-methoxycinnamate

Base Information

• Chemical Name: Methyl p-methoxycinnamate
• CAS No.: 832-01-9
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.214
• Hs Code.: 2918999090
• European Community (EC) Number: 212-614-8
• DSSTox Substance ID: DTXSID401312296
• Wikidata: Q105284930,Q104199299
• Mol file: 832-01-9.mol

Synonyms:4-methoxycinnamate methyl ester;4-methoxycinnamate methyl ester, (E)-isomer;4-methoxycinnamate methyl ester, (Z)-isomer;4-methoxymethyl cinnamate

Chemical Property of Methyl p-methoxycinnamate

Chemical Property:

• Vapor Pressure: 0.000594mmHg at 25°C
• Melting Point: 89-90 °C
• Refractive Index: 1.546
• Boiling Point: 310.6 °C at 760 mmHg
• Flash Point: 126.9 °C
• PSA: 35.53000
• Density: 1.102 g/cm³
• LogP: 1.88140
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 192.078644241
• Heavy Atom Count: 14
• Complexity: 203

Purity/Quality:

≥98% ^*data from raw suppliers

4-MethoxycinnamicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)C=CC(=O)OC

Technology Process of Methyl p-methoxycinnamate

There total 59 articles about Methyl p-methoxycinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

para-iodoanisole (696-62-8) + acrylic acid methyl ester (292638-85-8,9003-21-8,96-33-3) → methyl p-methoxycinnamate (832-01-9,3901-07-3,19310-29-3)

Guidance literature:

With hollow carbonnanonets supported palladium nanoparticles; potassium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 1h; Time;

DOI:10.1039/c2cy20562a

Reference yield: 99.0%

methanol (67-56-1) + 3-(4'-methoxyphenyl)propenoic acid (830-09-1) → methyl p-methoxycinnamate (832-01-9,3901-07-3,19310-29-3)

Guidance literature:

3-(4'-methoxyphenyl)propenoic acid; With boron trichloride;

methanol;

DOI:10.1016/S0040-4039(01)00602-5

Reference yield: 98.0%

acetic acid methyl ester (79-20-9) + 4-methoxy-benzaldehyde (123-11-5) → methyl p-methoxycinnamate (832-01-9,3901-07-3,19310-29-3)

Guidance literature:

With titanium tetrachloride; di-n-propylamine; In toluene; at 0 - 20 ℃; for 5h;

upstream raw materials:

methanol

p-methoxycinnamoyl chloride

p-Coumaric Acid

methyl iodide

Downstream raw materials:

2,3-dibromo-3-(4-methoxyphenyl)propionic acid methyl ester

3-amino-3-(4-methoxyphenyl)propionic acid

p-methoxycinnamyl alcohol

methyl 3-(4-methoxyphenyl)propionate