4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-

Base Information

Chemical Name:4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-
CAS No.:37389-83-6
Molecular Formula:C14H18N4O4
Molecular Weight:306.321
Hs Code.:
Mol file:37389-83-6.mol

Synonyms:2,4-Diamino-5-(3,4,5-trimethoxy-benzyl)-6-hydroxypyrimidin;2,4-Diamino-6-hydroxy-5-(3',4',5'-trimethoxybenzyl)pyrimidin;2,4-diamino-5-(3',4',5'-trimethoxybenzyl)-6-hydroxypyrimidine;2,6-diamino-5-(3,4,5-trimethoxy-benzyl)-3H-pyrimidin-4-one;

Suppliers and Price of 4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-

Chemical Property:

PSA：125.74000
LogP:2.12560

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]-

There total 7 articles about 4(1H)-Pyrimidinone, 2,6-diamino-5-[(3,4,5-trimethoxyphenyl)methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29958-02-9
2-cyano-3-(3,4,5-trimethoxy-phenyl)propionic acid ethyl ester

: 113-00-8
guanidine nitrate

: 37389-83-6
2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-6-hydroxy-pyrimidine

Guidance literature:: 2-cyano-3-(3,4,5-trimethoxy-phenyl)propionic acid ethyl ester; guanidine nitrate; With acetic anhydride; In N,N-dimethyl-formamide; for 1h; Reflux;

With 15-crown-5; sodium methylate; In N,N-dimethyl-formamide; for 1h; Reflux;

Reference yield:

: α-cyano-3,4,5-trimethoxy-dihydrocinnamimide

: 124-46-9,20734-13-8,100224-74-6,593-85-1,90332-86-8,3425-08-9
guanidine hydrogen carbonate

: 113-00-8
guanidine nitrate

: 37389-83-6
2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-6-hydroxy-pyrimidine

Guidance literature:: With hydrogenchloride; sodium; In methanol; water;

Reference yield:

: 86-81-7
3,4,5-trimethoxy-benzaldehyde

: 37389-83-6
2,4-diamino-5-(3',4',5'-trimethoxy-benzyl)-6-hydroxy-pyrimidine

Guidance literature:: Multi-step reaction with 3 steps

1: 95 percent / TEBA / 1 h / 85 °C

2: 90 percent / H₂ / 10 percent Pd/C / ethyl acetate / 2.5 h

3: Na / methanol / 12 h / Heating

With N-benzyl-N,N,N-triethylammonium chloride; hydrogen; sodium; palladium on activated charcoal; In methanol; ethyl acetate;