(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol

Base Information

Chemical Name:(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol
CAS No.:444615-64-9
Molecular Formula:C12H10F3NO2S
Molecular Weight:289.278
Hs Code.:2934100090
DSSTox Substance ID:DTXSID70474971
Wikidata:Q82305167
Mol file:444615-64-9.mol

Synonyms:(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol;444615-64-9;[5-(HYDROXYMETHYL)-2-[4-(TRIFLUOROMETHYL)PHENYL]-1,3-THIAZOL-4-YL]METHANOL;{2-[4-(trifluoroMethyl)phenyl]-1,3-thiazole-4,5-diyl}diMethanol;{5-(Hydroxymethyl)-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methanol;SCHEMBL4808139;DTXSID70474971;A849454;{5-Hydroxymethyl-2-[4-(trifluoromethyl)phenyl]-1,3-thiazol-4-yl}methanol

Suppliers and Price of (2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol 95+%
1g
$ 614.00

Chemenu
(2-(4-(trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol 95%
1g
$ 580.00

American Custom Chemicals Corporation
(2-(4-(TRIFLUOROMETHYL)PHENYL)THIAZOLE-4,5-DIYL)DIMETHANOL 95.00%
5MG
$ 501.97

Alichem
(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol
1g
$ 510.00

Total 7 raw suppliers

Chemical Property of (2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol

Chemical Property:

PSA：81.59000
LogP:2.81350
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:289.03843422
Heavy Atom Count:19
Complexity:295

Purity/Quality:

97% ^*data from raw suppliers

(2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC(=C(S2)CO)CO)C(F)(F)F

Technology Process of (2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol

There total 3 articles about (2-(4-(Trifluoromethyl)phenyl)thiazole-4,5-diyl)dimethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 444615-63-8
diethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-dicarboxylate

: 444615-64-9
{2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-diyl}dimethanol

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at -15 - -10 ℃; for 1h;
DOI:10.1021/jo061295n

Reference yield: 77.4%

: 444615-63-8
diethyl 2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-dicarboxylate

: 67-56-1
methanol

: 444615-64-9
{2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-diyl}dimethanol

Guidance literature:: With sodium tetrahydroborate; acetic acid; In tetrahydrofuran; at 45 - 50 ℃; for 3h;

Reference yield:

: 72505-21-6
4-trifluoromethylbenzthioamide

: 444615-64-9
{2-[4-(trifluoromethyl)phenyl]-1,3-thiazole-4,5-diyl}dimethanol

Guidance literature:: Multi-step reaction with 2 steps

1: 83 percent / ethanol / 6 h / 67 - 69 °C

2: 81 percent / lithium aluminium hydride / tetrahydrofuran / 1 h / -15 - -10 °C

With lithium aluminium tetrahydride; In tetrahydrofuran; ethanol;
DOI:10.1021/jo061295n