N,N,5-Trimethylfurfurylamine

Base Information

• Chemical Name: N,N,5-Trimethylfurfurylamine
• CAS No.: 14496-35-6
• Molecular Formula: C8H13 N O
• Molecular Weight: 139.197
• Hs Code.: 2932190090
• European Community (EC) Number: 623-252-9
• DSSTox Substance ID: DTXSID60162850
• Nikkaji Number: J577.607D
• Wikidata: Q83031609
• Mol file: 14496-35-6.mol

Synonyms:2-N,N-dimethylaminomethyl-5-methylfuran;DMAMMF

Chemical Property of N,N,5-Trimethylfurfurylamine

Chemical Property:

• Vapor Pressure: 3.83mmHg at 25°C
• Melting Point: 161-164 °C
• Refractive Index: 1.4640
• Boiling Point: 150.5°Cat760mmHg
• PKA: 8.42±0.28(Predicted)
• Flash Point: 44.8°C
• PSA: 16.38000
• Density: 0.959g/cm³
• LogP: 1.64960
• Storage Temp.: Refrigerator
• XLogP3: 1.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 139.099714038
• Heavy Atom Count: 10
• Complexity: 103

Purity/Quality:

97% ^*data from raw suppliers

N,N,5-Trimethylfurfurylamine ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 34-36/37/38-10
• Safety Statements: 26-36/37/39-45-36-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(O1)CN(C)C

Technology Process of N,N,5-Trimethylfurfurylamine

There total 8 articles about N,N,5-Trimethylfurfurylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

2-methylfuran (534-22-5) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + N,N-dimethylammonium chloride (506-59-2) → N,N-dimethyl-1-(5-methylfuran-2-yl)methanamine (14496-35-6)

Guidance literature:

formaldehyd; N,N-dimethylammonium chloride; With hydrogenchloride; In water; at 50 ℃; for 1h;

2-methylfuran; In water; at 28 - 60 ℃; for 6h; Temperature;

Reference yield: 91.0%

5-Methylfurfural (620-02-0) + hexamethylenetetramine (100-97-0) → N,N-dimethyl-1-(5-methylfuran-2-yl)methanamine (14496-35-6)

Guidance literature:

With hydrogen; nickel(II) acetate tetrahydrate; In ethanol; at 140 ℃; under 30003 Torr; Autoclave; Green chemistry;

DOI:10.1002/cjoc.202000004

Reference yield: 84.0%

2-methylfuran (534-22-5) + N,N-dimethyl(methylene)ammonium chloride (30354-18-8) → N,N-dimethyl-1-(5-methylfuran-2-yl)methanamine (14496-35-6)

Guidance literature:

In acetonitrile; for 72h; Ambient temperature;

DOI:10.1016/S0040-4039(00)86064-5

upstream raw materials:

2-methylfuran

dimethyl amine

2,5-dimethylfuran

N,N-dimethyl(methylene)ammonium chloride

Downstream raw materials:

[2.2](2.5)furanocyclophane

2-hydroxy-3-methylcyclopent-2-en-1-one

[(5-Methyl-2-furyl)methyl](triphenyl)phosphonium iodide

5-methyl-2-(N-piperidinylmethyl)furan