5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one

Base Information

Chemical Name:5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one
CAS No.:60438-04-2
Molecular Formula:C12H12N2O2
Molecular Weight:216.239
Hs Code.:
NSC Number:94994
DSSTox Substance ID:DTXSID10294175
Wikidata:Q82033301

Synonyms:5-(benzyloxy)-2-methylpyrimidin-4(3h)-one;60438-04-2;NSC94994;SCHEMBL21040513;DTXSID10294175;NSC-94994;AKOS026715782;F2147-2353

Suppliers and Price of 5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
Density:1.19g/cm³
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:216.089877630
Heavy Atom Count:16
Complexity:328

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C(=O)N1)OCC2=CC=CC=C2

Technology Process of 5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one

There total 6 articles about 5-(Benzyloxy)-2-methylpyrimidin-4(3h)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 31600-43-8
methyl 2-(benzyloxy)acetate

: 124-42-5
acetamidine hydrochloride

: 109-94-4
formic acid ethyl ester

: 60438-04-2
5-(benzyloxy)-2-methylpyrimidin-4-ol

Guidance literature:: methyl 2-(benzyloxy)acetate; formic acid ethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; for 0.75h;

acetamidine hydrochloride; With sodium ethanolate; In ethanol; at 100 ℃; for 16h;

Reference yield: 44.0%

: 31600-43-8
methyl 2-(benzyloxy)acetate

: 141-52-6
sodium ethanolate

: 109-94-4
formic acid ethyl ester

: 60438-04-2
5-(benzyloxy)-2-methylpyrimidin-4-ol

Guidance literature:: methyl 2-(benzyloxy)acetate; formic acid ethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 - 50 ℃; for 0.75h;

sodium ethanolate; With acetamidine hydrochloride; sodium; In ethanol; at 0 - 20 ℃; for 0.5h;

With acetamidine; In ethanol; at 100 ℃; for 16h;

Reference yield:

: 100-39-0
benzyl bromide

: 60438-04-2
5-(benzyloxy)-2-methylpyrimidin-4-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: sodium hydride / tetrahydrofuran; mineral oil / 0.75 h / 0 °C

1.2: 16 h / 0 - 20 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 0.75 h

2.2: 16 h / 100 °C

With sodium hydride; In tetrahydrofuran; mineral oil;