N,N-Dimethylglycine methyl ester

Base Information

• Chemical Name: N,N-Dimethylglycine methyl ester
• CAS No.: 7148-06-3
• Molecular Formula: C5H11 N O2
• Molecular Weight: 117.148
• Hs Code.: 2922499990
• European Community (EC) Number: 678-389-7
• NSC Number: 29651
• DSSTox Substance ID: DTXSID60221693
• Nikkaji Number: J127.903C
• Wikidata: Q83099620
• Mol file: 7148-06-3.mol

Synonyms:N,N-Dimethylglycine methyl ester;7148-06-3;methyl 2-(dimethylamino)acetate;Glycine, N,N-dimethyl-, methyl ester;Methyl (dimethylamino)acetate;Methyl (dimethylamino) acetate;BRN 1744788;N,N-Dimethyl-glycine methyl ester;dimethylglycine methyl ester;(CH3)2NCH2COOCH3;methyl 2-dimethylaminoacetate;SCHEMBL196772;methyl2-(dimethylamino)acetate;n,n-dimethylglycinemethyl ester;Dimethylaminoessigsauremethylester;LRZFEBJUJIQVDQ-UHFFFAOYSA-;DTXSID60221693;Glycine,N-dimethyl-, methyl ester;N,N-Dimethyl glycine methyl ester;NSC29651;MFCD00059303;NSC 29651;NSC-29651;AKOS003961597;(Dimethylamino)acetic acid methyl ester;GS-5488;HY-W141886;LS-72565;CS-0201680;D0257;FT-0693595;H10578;3-04-00-01125 (Beilstein Handbook Reference)

Chemical Property of N,N-Dimethylglycine methyl ester

Chemical Property:

• Vapor Pressure: 15.1mmHg at 25°C
• Refractive Index: 1.4120
• Boiling Point: 134-135oC
• PKA: 7.22±0.28(Predicted)
• Flash Point: 38oC
• PSA: 29.54000
• Density: 0,95 g/cm3
• LogP: -0.27900
• Storage Temp.: Refrigerator
• Sensitive.: Air Sensitive
• Water Solubility.: Soluble in water.
• XLogP3: 0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 117.078978594
• Heavy Atom Count: 8
• Complexity: 80.5

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N-Dimethylglycine Methyl Ester ^*data from reagent suppliers

Safty Information:

• Statements: 10-36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Nitrogen Compounds -> Other Nitrogen Compounds
• Canonical SMILES: CN(C)CC(=O)OC
• Uses: N,N-Dimethylglycine methyl ester is used as a biochemical for proteomics research. It is also used as chemical and pharmaceutical intermediate.

Technology Process of N,N-Dimethylglycine methyl ester

There total 2 articles about N,N-Dimethylglycine methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2-diazo-N,N-dimethyl-acetamide (62285-47-6) → 1-methylazetidine-2-one (2679-13-2) + methoxy acetic acid dimethylamide (4128-76-1) + N,N-dimethylglycine methyl ester (7148-06-3)

Guidance literature:

Irradiation;

DOI:10.1021/jo00319a010

Reference yield:

betaine (107-43-7) → N,N-dimethylglycine methyl ester (7148-06-3) + dimethyl amine (124-40-3) + trimethylamine (75-50-3)

Guidance literature:

at 300 ℃; Produkt₅:Methylamin, Produkt₆:Formaldehyd, Produkt₇:Pyrrol(?);

Reference yield: 99.0%

N,N-dimethylglycine methyl ester (7148-06-3) → N,N-dimethylglycine hydrochoride (2491-06-7)

Guidance literature:

With hydrogenchloride; for 24h; Heating;

DOI:10.1021/jm00156a024

upstream raw materials:

methanol

2-diazo-N,N-dimethyl-acetamide

betaine

Downstream raw materials:

betaine

dimethylamino-2-methyl-2-butanol

(carboxymethyl)-trimethylammonium hydroxide

betain methyl ester iodide

Refernces