potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

Base Information

Chemical Name:potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate
CAS No.:1408001-09-1
Molecular Formula:C₁₅H₁₄F₄NO₂S*K
Molecular Weight:387.44
Hs Code.:

Synonyms:potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

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Chemical Property of potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

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Technology Process of potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

There total 1 articles about potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 655-32-3
2,2,2-trifluoro-1-(4-fluorophenyl)ethanone

: (R)-methyl2-amino-3-((cyclopropylmethyl)thio)propanoate hydrochloride

: 1408001-09-1
potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

Guidance literature:: With potassium carbonate; In isopropyl alcohol; acetonitrile;

Reference yield:

: zinc(II) tetrahydroborate

: 124-38-9,18923-20-1
carbon dioxide

: 1408001-09-1
potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

: 849094-18-4
(R)-3-((cyclopropylmethyl)thio)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

Guidance literature:: With hydrogenchloride; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; acetonitrile;

Reference yield:

: 1408001-09-1
potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

: 849094-11-7
(R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / zinc(II) chloride / 1,2-dimethoxyethane; acetonitrile; lithium borohydride

2: dihydrogen peroxide / ethyl acetate; toluene; hexane

With hydrogenchloride; dihydrogen peroxide; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; hexane; ethyl acetate; toluene; acetonitrile;