N-Methylethylenediamine

Base Information

• Chemical Name: N-Methylethylenediamine
• CAS No.: 109-81-9
• Molecular Formula: C3H10 N2
• Molecular Weight: 74.1258
• Hs Code.: 29212900
• European Community (EC) Number: 203-707-4
• UNII: V3P6B23FWK
• DSSTox Substance ID: DTXSID5059377
• Nikkaji Number: J93.028H
• Wikidata: Q81988771
• Mol file: 109-81-9.mol

Synonyms:N-Methylethylenediamine;109-81-9;1,2-Ethanediamine, N-methyl-;2-Aminoethylmethylamine;N1-Methylethane-1,2-diamine;N-Methyl-1,2-ethanediamine;2-(Methylamino)ethylamine;N-Methyldiaminoethane;N-Methylethanediamine;N'-methylethane-1,2-diamine;ETHYLENEDIAMINE, N-METHYL-;N-Methylethylidenediamine;N-methylethane-1,2-diamine;(2-aminoethyl)(methyl)amine;BRN 0878141;1,2-Ethanediamine, N1-methyl-;N-methyl ethylenediamine;EINECS 203-707-4;V3P6B23FWK;AI3-26642;4-04-00-01170 (Beilstein Handbook Reference);2-Methylaminoethylamine;methylethylenediamine;N-methyl-ethylendiamine;n-methylethyl enediamine;N-methyl-ethylenediamine;N-methylethylene diamine;N-methylethylene-diamine;2-methylamino-ethylamine;N-methyl ethylene diamine;N-methyl-ethylene-diamine;(2-aminoethyl)methylamine;UNII-V3P6B23FWK;N-methyl-1,2-diaminoethane;N-Methyl-1,2 diaminoethane;2-Methylaminoethylamine 95%;N-methyl-ethane-1,2-diamine;N-Methylethylenediamine, 95%;N'-methyl-ethane-1,2-diamine;N1-methyl-ethane-1,2-diamine;1,2-Ethanediamine,N1-methyl-;DTXSID5059377;KFIGICHILYTCJF-UHFFFAOYSA-;N-methyl-N-(2-aminoethyl)amine;STR05736;BBL027689;MFCD00008165;STL370318;AKOS009156815;SB66403;LS-68479;CS-0108722;FT-0631611;M0518;EN300-62146;D76853;A802092;J-002333

Chemical Property of N-Methylethylenediamine

Chemical Property:

• Appearance/Colour: clear very slight yellow liquid
• Vapor Pressure: 19.4mmHg at 25°C
• Refractive Index: n20/D 1.4395(lit.)
• Boiling Point: 114-117 °C(lit.)
• PKA: pK1:6.86(＋1);pK2:10.15(＋1) (25°C)
• Flash Point: 106 °F
• PSA: 38.05000
• Density: 0.85 g/mL at 20 °C(lit.)
• LogP: 0.25570
• Storage Temp.: Flammables area
• Sensitive.: Air Sensitive & Hygroscopic
• XLogP3: -1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 74.084398327
• Heavy Atom Count: 5
• Complexity: 14.4

Purity/Quality:

99% ^*data from raw suppliers

N-Methylethylenediamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C
• Statements: 10-34-37
• Safety Statements: 26-36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Nitrogen Compounds -> Amines, Aliphatic
• Canonical SMILES: CNCCN
• Uses: N-Methylethylenediamine undergoes condensation with pyridine-2-carboxaldehyde to form an imine.

Technology Process of N-Methylethylenediamine

There total 22 articles about N-Methylethylenediamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.2%

methanol (67-56-1) + ethylenediamine (107-15-3,85404-18-8) → N-methyl-ethane-1,2-diamine (109-81-9)

Guidance literature:

With hydrogen; at 160 ℃; under 7500.75 Torr;

DOI:10.2478/s11696-012-0140-8

Reference yield: 43.1%

2-chloroethanamine hydrochloride (870-24-6) → N-methyl-ethane-1,2-diamine (109-81-9)

Guidance literature:

With potassium hydroxide; methylamine; In water;

Reference yield:

methanol (67-56-1) + ethylenediamine (107-15-3,85404-18-8) → N,N-dimethylethylenediamine (108-00-9) + N-methyl-ethane-1,2-diamine (109-81-9) + N,N`-dimethylethylenediamine (110-70-3)

Guidance literature:

With Cs-P-Si; at 300 ℃; under 61504.9 Torr;

DOI:10.1021/ja048557s

upstream raw materials:

N-[2-(N-methyl-anilino)-ethyl]-N-nitroso-acetamide

2-amino-ethanol hydrochloride

methylamine hydrochloride

2-bromoethylamine hydrobromide

Downstream raw materials:

1-Methyl-2-p-tolyl-imidazolidine

2-[(4-t-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1-methylimidazole

2-Mercapto-1-methyl-4,5-dihydroimidazole

N'-methyl-N-(3-methylbenzyl)ethylenediamine

Refernces

• 1、 Huang, Jia-Min,Xu, Lu-Feng,Qian, Chao,Chen, Xin-Zhi. "N-alkylation of ethylenediamine with alcohols catalyzed by CuO-NiO/γ-Al2O3". . p. 304 - 307. Retrieved 2012.
• 2、 Wang, Wenwen,Wei, Ruisong,Yin, Guohui,Tian, Jun,Duan, Yifan,Chen, Ligong,Li, Yang. "The synthesis of asymmetric ethylenediamine derivatives catalyzed by ion-exchange resins". . p. 4511 - 4522. Retrieved 2015/06/30.