N-Methylpropylamine

Base Information

• Chemical Name: N-Methylpropylamine
• CAS No.: 627-35-0
• Molecular Formula: C4H11N
• Molecular Weight: 73.138
• Hs Code.: 29211990
• Mol file: 627-35-0.mol

Synonyms:Propylamine,N-methyl- (6CI,7CI,8CI);Methylpropylamine;N-Methyl-1-propanamine;N-Methyl-1-propylamine;N-Methyl-n-propylamine;N-Methylpropanamine;

Chemical Property of N-Methylpropylamine

Chemical Property:

• Appearance/Colour: clear colorless liquid
• Vapor Pressure: 160mmHg at 25°C
• Melting Point: -60.4°C (estimate)
• Refractive Index: n20/D 1.394(lit.)
• Boiling Point: 65.1 °C at 760 mmHg
• PKA: 10.76±0.10(Predicted)
• Flash Point: −25 °F
• PSA: 12.03000
• Density: 0.707 g/cm³
• LogP: 1.00670
• Storage Temp.: Flammables area
• Solubility.: Chloroform, Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Methyl-1-propanamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): FC
• Hazard Codes: F,C
• Statements: 11-34
• Safety Statements: 16-26-27-36/37/39-45-25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: A naturally occurring nitrostable secondary amine found in tabacco smoke condensate.

Technology Process of N-Methylpropylamine

There total 17 articles about N-Methylpropylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

propionaldehyde (123-38-6) + methylamine (74-89-5) → propan-1-ol (71-23-8) + methyl-n-propylamine (627-35-0)

Guidance literature:

With potassium phosphate; at 20 ℃; Product distribution; electrochemical reductive amination; var. pH, var. current densities and electrodes, var. aldehydes;

Reference yield: 45.0%

N-benzylidenepropylamine (6852-55-7) + (ethoxycarbonylmethyl)dimethylsulfonium bromide (5187-82-6) → methyl-n-propylamine (627-35-0) + 1-methylthio-3-phenyl-1,2-cyclopropanedicarboxylic acid diethyl ester (94117-87-0)

Guidance literature:

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In tetrahydrofuran; at 20 ℃; for 4h;

DOI:10.1007/BF01455482

Reference yield: 25.0%

methyl-propyliden-amine (6898-68-6) → methyl-n-propylamine (627-35-0)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol; at 20 ℃; under 2660 Torr;

DOI:10.1002/ardp.19843170306

upstream raw materials:

pyridine

N,N-dimethylaminopropane

dibenzoyl peroxide

methyl-propyliden-amine

Downstream raw materials:

N'-(3-chloro-phenyl)-N-methyl-N-propyl-urea

3-(2,4-Dimethyl-phenyl)-1-methyl-1-propyl-thiourea

3-(4-Bromo-2-methyl-phenyl)-1-methyl-1-propyl-thiourea

3-[4-(4-Methoxy-phenoxy)-phenyl]-1-methyl-1-propyl-thiourea

Refernces

• 1、 Stein, Mario,Breit, Bernhard. "Catalytic hydrogenation of amides to amines under mild conditions". supporting information. p. 2231 - 2234. Retrieved 2013/03/28.
• 2、 Lum, Rachel C.,Grabowski, Joseph J.. "Carbon versus phosphorus site selectivity in the gas-phase anion-molecule reactions of dimethyl methylphosphonate". . p. 7823 - 7832. Retrieved 2007/10/02.